Results 61 to 70 of about 395,686 (299)

A Review on Adhesively Bonded Aluminium Joints in the Automotive Industry

open access: yesMetals, 2020
The introduction of adhesive bonding in the automotive industry is one of the key enabling technologies for the production of aluminium closures and all-aluminium car body structures.
Francesca Cavezza   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Análisis descriptivo de la dinámica del surf como práctica social

open access: yesTelos: Revista de Estudios Interdisciplinarios en Ciencias Sociales, 2014
En este trabajo de investigación, la cultura del surf es analizada desde la teoría de la práctica social (Giraldo y Halliday 2012, Shove et al., 2012). Para este fin, se estudiaron cada uno de los elementos que conforman la práctica y la forma como estos
Oscar Naranjo Del Giudice   +1 more
doaj  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Detección de movimiento en tiempo real utilizando flujo óptico

open access: yesVisión Electrónica, 2015
Se muestra la implementación de algoritmos de flujo óptico y extracción de características para el reconocimiento y detección de objetos en tiempo real de una secuencia de imágenes.
Jonathan Avendaño Pérez   +3 more
doaj   +1 more source

Surf zone currents and influence on surfability [PDF]

open access: yes, 2003
Surfing headlands are shallow and exposed coastal features that provide a specific form of breaking wave allowing a board-rider to ride on the unbroken wave face.
Black, Kerry P.   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Detection of human finger joints in ultrasound images: structure and optimization [PDF]

open access: yesInternational Journal of Electronics and Telecommunications
Synovitis is the inflammation of a synovial membrane surrounding a joint. Its assessment is an important step in the diagnosis and treatment of rheumatoid arthritis.
Artur Bąk   +5 more
doaj   +1 more source

Summer Cook Associate Professor of Kinesiology (COLA) travels to Australia [PDF]

open access: yes, 2016
I was partially supported by a CIE International development grant to travel to Perth, Australia for one month in 2016. Dr. Timothy Fairchild, a colleague and friend, invited me to visit the Department of Psychology and Exercise Science at Murdoch ...
Cook, Summer B.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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