Results 91 to 100 of about 9,174,816 (293)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Fast track on the surface active agents involved in nanoemulsion for drug delivery

Al-Mustansiriyah Journal of Pharmaceutical Sciences
Nanoemulsions (NEs) are colloidal dispersion systems made of two immiscible liquids combined with co-surfactants and surfactants (emulsifying agents), to form a thermodynamically stable. Numerous synthetic and natural compounds with the aim of enhancing
Sara Abdullah Challoob, Nidhal Khazaal Maraie, Issraa AL-Obaidi   +2 more
doaj   +1 more source

Sustained antibacterial coating with graphene oxide ultrathin film combined with cationic surface-active agents in a wet environment. [PDF]

Sci Rep, 2022
Miyaji H, Kanemoto Y, Hamamoto A, Shitomi K, Nishida E, Kato A, Sugaya T, Tanaka S, Aikawa N, Kawasaki H, Gohda S, Ono H.   +11 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Surface active agents as environmental pollutants

, 2020
Površinski aktivne tvari su organski spojevi koji se dijele na anionske, kationske, neionske i amfoterne. Primjenjuju se kao sastojci mnogih proizvoda za higijenu i dezinfekciju u kućanstvu i industriji. Djeluju biocidno, kao dezinficijensi, emulgatori i
Remetović, Magdalena
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Development of highly porous calcium phosphate bone cements applying nonionic surface active agents. [PDF]

RSC Adv, 2021
Cichoń E, Mielan B, Pamuła E, Ślósarczyk A, Zima A.   +4 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Influence of chemical agents on the surface area and porosity of active carbon hollow fibers [PDF]

Journal of the Serbian Chemical Society, 2011
Active carbon hollow fibers were prepared from regenerated polysulfone hollow fibers by chemical activation using: disodium hydrogen phosphate 2-hydrate, disodium tetraborate 10-hydrate, hydrogen peroxide, and diammonium hydrogen phosphate.
LJILJANA M. KLJAJEVIĆ, VLADISLAVA M. JOVANOVIĆ, SANJA I. STEVANOVIĆ, ŽARKO D. BOGDANOV, BRANKA V. KALUDJEROVIĆ   +4 more
doaj  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source