Results 71 to 80 of about 2,141,685 (338)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
SPERMICIDAL ACTIVITY OF SURFACE-ACTIVE AGENTS [PDF]
Reproduction, 1962 The spermicidal activities against human spermatozoa of a range of non-ionic, anionic and cationic surface-active agents have been determined with the method of Baker, Ransom & Tynen (1937). Although it has been concluded that surface-tension-lowering properties do not directly influence spermicidal power, the surfacetension/concentration curves of a ...
C, HARVEY, R E, STUCKEY
openaire +2 more sources
Tipstreaming of a drop in simple shear flow in the presence of surfactant [PDF]
, 2010 We have developed a multi-phase SPH method to simulate arbitrary interfaces containing surface active agents (surfactants) that locally change the properties of the interface, such the surface tension coefficient.
Adami, S., Adams, N. A., Hu, X. Y.
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Hemolysis by Nonionic Surface-active Agents
YAKUGAKU ZASSHI, 1966 The hemolytic actions of polyoxyethylene glycol monododecyl ethers, C12H25-(C2H4O)nOH, have been studied. The amount required of these agents to produce lysis was found to be linearly related to the red cell concentration within experimental error. This was interpreted as showing the significant role of the adsorption of nonionic agent molecules onto ...
T, Kondo, M, Tomizawa
openaire +4 more sources
, 1974 An anti-fog composition is described for the prevention of fogging on surfaces such as space helmet visors, spacecraft windows, and windshields.
Carmin, D. L., Jr., Morrison, H. D.
core +1 more source
DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown [PDF]
, 2011 Damage-associated molecular patterns (DAMPs) or cell death associated molecular patterns (CDAMPs) are a subset of endogenous intracellular molecules that are normally hidden within living cells but become either passively released by primary and ...
Agostinis, Patrizia +3 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Biocide activity of microfiber mops with and without silver after contamination
Brazilian Journal of Infectious DiseasesOBJECTIVE: The purpose of the present research was to compare the residual microbial load in Solo System microfiber mops with silver and in normal microfiber mops without silver to see whether those with the silver prevent bacterial proliferation and ...
Sonia De Lorenzi +3 more
doaj +1 more source