Results 51 to 60 of about 9,174,816 (293)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

How to join a wave: decision-making processes in shimmering behavior of Giant honeybees (Apis dorsata). [PDF]

open access: yesPLoS ONE, 2012
Shimmering is a collective defence behaviour in Giant honeybees (Apis dorsata) whereby individual bees flip their abdomen upwards, producing Mexican wave-like patterns on the nest surface.
Gerald Kastberger   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A review of the best-selling conventional toothpastes and herbal-based natural toothpastes in Turkey

open access: yesAdıyaman Üniversitesi Sağlık Bilimleri Dergisi
Aim: The aim is to know the ingredients of the most well-known and best-selling toothpastes in the market in Turkey, to compare conventional and herbal-based natural toothpastes and to reveal their differences.
Şahin Altuğ, Yasin Çiçek
doaj   +1 more source

Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest

open access: yesGrasas y Aceites, 2006
T2-Hydroxyheptadecanoic acid chloride (2) reacted with anthranilic acid to produce 2-substituted-3,1-benzoxazin-4-one (3) which was used as starting material to synthesize some condensed and non-condensed heterocyclic compounds by reaction with nitrogen ...
A. M. F. Eissa, R. El-Sayed
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Surface Tension of Surface Active Agents in Multicomponent Fusion

open access: yes, 2005
katedra: KTC; rozsah: 85 s., 5 prílohTáto diplomová práca sa zaoberá stanovením povrchového napätia čistých roztokov aniónaktívnych, neiónogenných a amfoterných povrchovo aktívnych látok ako aj ich kombinácií s ďalšími látkami: NaCl, močovinou a ...
Bachurová, Marcela, Tomehová, Marcela
core   +1 more source

Biocide activity of microfiber mops with and without silver after contamination

open access: yesBrazilian Journal of Infectious Diseases
OBJECTIVE: The purpose of the present research was to compare the residual microbial load in Solo System microfiber mops with silver and in normal microfiber mops without silver to see whether those with the silver prevent bacterial proliferation and ...
Sonia De Lorenzi   +3 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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