Results 41 to 50 of about 2,141,685 (338)

Role of Surface Active Agents in Transferosome for Systemic Drug Delivery

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences
The recent utilization of transferosomes (a type of vesicular drug-carrier system) has shown promising results in enhancing the transport of drugs through the skin when administered topically.
Mohsin Hussein Abdulameer   +2 more
doaj   +1 more source

Mesoporous Silica Platforms with Potential Applications in Release and Adsorption of Active Agents

open access: yesMolecules, 2020
In recent years, researchers focused their attention on mesoporous silica nanoparticles (MSNs) owing to the considerable advancements of the characterization methods, especially electron microscopy methods, which allowed for a clear visualization of the ...
Cristina Chircov   +7 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Voltammetric determination of the critical micellar concentration of surfactants by using a boron doped diamond anode [PDF]

open access: yes, 2010
The electrochemistry of three surfactants has been studied by voltammetry at boron doped diamond (BDD) electrode in sodium sulphate solutions. The electrochemical behaviour of these surfactants is characterized by an oxidation signal (peak or wave ...
Groenen Serrano, Karine   +2 more
core   +2 more sources

Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]

open access: yes, 2020
Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I   +3 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Optimization of cleansing oil formulation containing polyglyceryl-6 caprylate and polyglyceryl-4 caprate using the response surface method

open access: yesİstanbul Journal of Pharmacy
Background and Aims: Natural raw materials used in skin cleansing products have recently become popular. In this study, natural-origin raw materials were used to develop an oil-based cleanser formulation with high foaming ability and stable properties ...
Ayşenur Kılıç, Burak Çelik
doaj   +1 more source

Cytotoxicity evaluation of combination irrigant regimens with MTAD on two different cell lines

open access: yesContemporary Clinical Dentistry, 2018
Background: Effective management of smear layer ensures adequate clinical success. Use of sodium hypochlorite (NaOCl)/ethylenediaminetetraacetic acid regimen has been the gold standard with limitations.
Manikandan Ravinanthanan   +3 more
doaj   +1 more source

The solubilization of mitochondrial protein by nonionic surface active agents [PDF]

open access: yes, 1966
LD2668 .T4 1966 S971Master of ...
Swain, Louis Martin.
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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