Results 81 to 90 of about 7,165,449 (296)

Integrated waveguide and nanostructured sensor platform for surface-enhanced Raman spectroscopy

, 2014
Limitations of current sensors include large dimensions, sometimes limited sensitivity and inherent single-parameter measurement capability. Surface-enhanced Raman spectroscopy can be utilized for environment and pharmaceutical applications with the ...
Pollard, M., Kalsi, S., Oo, Swe Zin, Pearce, S., Chen, R., Charlton, M.D.B   +5 more
core   +1 more source

Modelling fluorescence quenching in systems with restricted diffusion: applications to oligonucleotides and polypeptides [PDF]

, 2004
The objectives of the present thesis are 1) to systematically develop a series of models and theoretical expressions for the diffusion-controlled reaction, which can be used to analyze the time-resolved fluorescence data in systems where the diffusion is
Wang, Xiaojuan
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Surface-enhanced Raman spectroscopy using silver impregnated polycarbonate substrates [PDF]

, 2007
Novel substrates based on noble metal nanoparticles are currently the subject of extensive research in fields such as biological sensing, medicine, spectroscopy and nano-photonics due to the large electromagnetic fields generated in the vicinity of the ...
Peacock, A.C., Sazio, Pier-John, Howdle, S.M., Lagonigro, L., Hasell, T., Brown, P.D.   +5 more
core   +2 more sources

Metal-enhanced excimer (P-type) fluorescence

, 2008
In this Letter, we report the first observation of metal-enhanced excimer (P-type) fluorescence from pyrene. Pyrene in close proximity to silver island films (SIFs) shows enhanced pyrene excimer emission with a ≈2.5-fold higher emission intensity ...
Zhang, Yongxia, Aslan, Kadir, Previte, Michael J. R., Geddes, Chris   +3 more
core   +1 more source

Raman Chemical Imaging of Chromate Reduction Sites in a Single Bacterium Using Intracellularly Grown Gold Nanoislands [PDF]

, 2011
Imaging live molecular events within micro-organisms at single-cell resolution would deliver valuable mechanistic information much needed in understanding key biological processes. We present a surface-enhanced Raman (SERS) chemical imaging strategy as a
Ravindranath, Sandeep, Irudayaraj, J., Kristene L. Henne, Dorothea K. Thompson, Henne, K. L., Sandeep P. Ravindranath, Joseph Irudayaraj, Thompson, Dorothea, Irudayaraj, Joseph, Ravindranath, S. P., Thompson, D. K., Henne, Kristene L.   +11 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Dual-Color Fluorescence Imaging of EpCAM and EGFR in Breast Cancer Cells with a Bull’s Eye-Type Plasmonic Chip

Sensors, 2017
Surface plasmon field-enhanced fluorescence microscopic observation of a live breast cancer cell was performed with a plasmonic chip. Two cell lines, MDA-MB-231 and Michigan Cancer Foundation-7 (MCF-7), were selected as breast cancer cells, with two ...
Shota Izumi, Shohei Yamamura, Naoko Hayashi, Mana Toma, Keiko Tawa   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Plasmonic and Dielectric Metasurfaces for Enhanced Spectroscopic Techniques

Biosensors
Spectroscopic techniques such as Surface-Enhanced Raman Scattering (SERS), Surface-Enhanced Infrared Absorption (SEIRA), and Surface-Enhanced Fluorescence (SEF) are essential analytical techniques used to study the composition of materials by analyzing ...
Borja García García, María Gabriela Fernández-Manteca, Dimitrios C. Zografopoulos, Celia Gómez-Galdós, Alain A. Ocampo-Sosa, Luis Rodríguez-Cobo, José Francisco Algorri, Adolfo Cobo   +7 more
doaj   +1 more source