Results 101 to 110 of about 7,165,449 (296)

Effectiveness of some herbals on initial enamel caries lesion

Asian Pacific Journal of Tropical Biomedicine, 2016
Objective: To evaluate the effectiveness of herbal medicaments such as ginger, rosemary and honey on remineralization of initial enamel lesion.
Gulcin Bilgin Gocmen, Funda Yanikoglu, Dilek Tagtekin, George K. Stookey, Bruce R. Schemehorn, Osman Hayran   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Metal-enhanced fluorescence from copper substrates

, 2007
In this letter, the authors report the observation of metal-enhanced fluorescence emission from fluorophores deposited on copper (Cu) substrates. Different thicknesses of Cu particulate films (from 1 to 5nm) were deposited onto glass slides using thermal
Zhang, Yongxia, Aslan, Kadir, Previte, Michael J. R., Geddes, Chris   +3 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Multiplexed evaluation of immunity against SARS-CoV-2 variants using surface enhanced fluorescence from a nanostructured plasmonic chip. [PDF]

J Nanobiotechnology, 2022
Hu R, Yang Y, Liu Y, Liao T, Liu Y, Tang J, Wang G, Wang G, Liang Y, Yuan J, Zhang B.   +10 more
europepmc   +1 more source

Plasmon Enhanced Fluorescence and Raman Scattering by [Au-Ag Alloy NP Cluster]@SiO2 Core-Shell Nanostructure

Frontiers in Chemistry, 2019
Silica-shell coated noble metal nanoparticles have shown a good performance in surface enhanced fluorescence and Raman scattering. However, silica-shell coated single noble nanoparticle cannot effectively enhance the optical signal due to the relative ...
Chengyun Zhang, Tingting Zhang, Zhenglong Zhang, Hairong Zheng   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Silver nanoparticle impregnated polycarbonate substrates for plasmonic applications [PDF]

, 2009
We present a new class of plasmonic substrates where silver nanoparticles are impregnated into a polycarbonate host.
S. Rohrmoser, Rohrmoser, S., Peacock, A.C., S. M. Howdle, Sazio, P.J.A., P.J.A. Sazio, T. Hasell, Howdle, S.M., Lagonigro, L., Lagoudakis, P.G., A.C. Peacock, P.G. Lagoudakis, Hasell, T., L. Lagonigro   +13 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Single-Molecule Detection of Optical Signals Using DNA-Based Plasmonic Nanostructures

Biosensors
Single-molecule optical signal detection provides high sensitivity and specificity for the detection of biomolecules and chemical substances, which is of significant importance in fields such as biomedicine, environmental monitoring, and materials ...
Renjie Niu, Jintian Shao, Mingnan Wu, Chang Liu, Jie Chao   +4 more
doaj   +1 more source