Results 71 to 80 of about 1,267,809 (297)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Antifungal Activities of Streptomyces blastmyceticus Strain 12-6 Against Plant Pathogenic Fungi
Streptomyces blastmyceticus strain 12-6 was isolated from a forest soil sample of Cheonan area on the basis of strong antifungal activities against plant pathogenic fungi. Butanol extracts of the cultural filtrates were active against C.
Yeon Ju Kim, Jae-heon Kim, Jae-Young Rho
doaj +1 more source
DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown [PDF]
Damage-associated molecular patterns (DAMPs) or cell death associated molecular patterns (CDAMPs) are a subset of endogenous intracellular molecules that are normally hidden within living cells but become either passively released by primary and ...
Agostinis, Patrizia +3 more
core +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
An anti-fog composition is described for the prevention of fogging on surfaces such as space helmet visors, spacecraft windows, and windshields.
Carmin, D. L., Jr., Morrison, H. D.
core +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
In order to solve the frosting and blockage problem of an air conditioning evaporator’s fin in winter, the nanoporous aluminum plates with low surface energy has been proposed in this paper, which are fabricated by an anodizing method and then ...
Song He +4 more
doaj +1 more source
Hemolysis by Nonionic Surface-active Agents
The hemolytic actions of polyoxyethylene glycol monododecyl ethers, C12H25-(C2H4O)nOH, have been studied. The amount required of these agents to produce lysis was found to be linearly related to the red cell concentration within experimental error. This was interpreted as showing the significant role of the adsorption of nonionic agent molecules onto ...
T, Kondo, M, Tomizawa
openaire +4 more sources
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Application of secondary of polymers and surface active agents to increase heavy oil recovery [PDF]
Basin on a comparison of laboratory results with results obtained by screening modelling, one of the most promising methods was selected – the method of oil displacement by means of the polymer injection.Water intended for the injection is thickened with
Karel Luner, Karel Bříza, Petr Bujok
doaj

