Results 121 to 130 of about 2,270,542 (300)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Process-Induced Crystal Surface Anisotropy and the Impact on the Powder Properties of Odanacatib
PharmaceuticsCrystalline active pharmaceutical ingredients with comparable size and surface area can demonstrate surface anisotropy induced during crystallization or downstream unit operations such as milling.
Isha Bade +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Synthesis and evaluation of some amine compounds having surface active properties as H2S scavenger
Egyptian Journal of Petroleum, 2014 In this work three H2S scavengers were prepared by reacting monoethanolamine with formaldehyde in different ratios (1:1, 2:1 and 2:3) to give MF1, MF2 and MF3, respectively.
Nadia G. Kandile +3 more
doaj +1 more source
How do the environmental extremes of Siberian permafrost soils shape the composition of the bacterial soil community? [PDF]
, 2007 Microbial communities in permafrost soils of the Siberian Arctic are exposed to extreme environmental conditions. The soils are frozen throughout the entire year except for the short summer period, when thawing of the uppermost 20 to 50 cm of the ...
Harder, J., Liebner, S., Wagner, Dirk
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Surface Composition and Adsorption Properties of Activated Carbon Cloth
Materials Science Forum, 2004 Surface properties of activated carbons have shown to play an important role in adsorption process. The presence of various functional groups (such as phenolic, carbonyl, carboxylic) on the carbon surface depends on the nature of its base component and the activation technique employed in the manufacturing process.
Vasiljevic, T +3 more
openaire +4 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Giant Low Surface Brightness Galaxies : Evolution in Isolation
, 2013 Giant Low Surface Brightness (GLSB) galaxies are amongst the most massive spiral galaxies that we know of in our Universe. Although they fall in the class of late type spiral galaxies, their properties are far more extreme.
Das, Mousumi
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source