Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers. [PDF]
PLoS ONE, 2011 Antibodies to polymorphic antigens expressed during the parasites erythrocytic stages are important mediators of protective immunity against P. falciparum malaria.
Louise Turner +6 more
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The Surface Antigens of Paramecium aurelia [PDF]
Journal of General Microbiology, 1956 SUMMARY: A surface antigen preparation obtained from Paramecium aurelia absorbs from a concentrated antiserum approximately 74% of the total antibody absorbed by the intact animal. An antiserum prepared against this preparation immobilized P. aurelia of the same serotype.
R, LITMAN +4 more
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TCR-T immunotherapy for the treatment of solid tumor: current status, challenges and future prospects [PDF]
Zhongguo aizheng zazhi, 2023 Engineered T cell receptor-T cell (TCR-T) therapy and chimeric antigen receptor-T cell (CAR-T) therapy are currently the two most effective ways of adoptive T cell therapy.
ZHENG Weitao, LI Hanluo, HU Kanghong
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Liposome-coupled antigens are internalized by antigen-presenting cells via pinocytosis and cross-presented to CD8 T cells. [PDF]
PLoS ONE, 2010 We have previously demonstrated that antigens chemically coupled to the surface of liposomes consisting of unsaturated fatty acids were cross-presented by antigen-presenting cells (APCs) to CD8+ T cells, and that this process resulted in the induction of
Yuriko Tanaka +4 more
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Persistence of Antigen on the Surface of Macrophages [PDF]
Nature, 1969 MOUSE peritoneal macrophages can take up and catabolize two different haemocyanins1,2. Although in tissue culture experiments most of these materials were broken down in a few hours after uptake, haemocyanin nevertheless elicited the formation of specific antibodies when the macrophages were transferred to syngeneic hosts, and the haemocyanin bound to ...
Unanue, E R, Cerottini, J, Bedford, M
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The MDM-2 Antagonist Nutlin-3 Promotes the Maturation of Acute Myeloid Leukemic Blasts
Neoplasia: An International Journal for Oncology Research, 2007 The small-molecule inhibitor of murine double minute (MDM-2), Nutlin-3, induced variable apoptosis in primary acute myeloid leukemia (AML) blasts, promoted myeloid maturation of surviving cells, as demonstrated by analysis of CD11 b, CD14 surface ...
Paola Secchiero +7 more
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Molecular mechanisms and biological importance of Plasmodium falciparum erythrocyte rosetting
Memorias do Instituto Oswaldo Cruz, 1992 Rosetting, i.e. the spontaneous binding of uninfected to malaria infected erythrocytes and endothelial cytoadherence may hinder the blood flow and lead to serve Plasmodium falciparum malaria.
Mats Wahlgren +4 more
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Helping tumour antigens to the surface [PDF]
Nature Reviews Cancer, 2019 Using high-resolution proteomics to analyse clinical samples from patients with advanced melanoma, Harel et al. show that the metabolic state of melanoma is associated with changes in antigen presentation-related proteins and thereby with response to immunotherapies.
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A surface antigen influenza vaccine: 2. Pyrogenicity and antigenicity [PDF]
Journal of Hygiene, 1976 SummaryConventional influenza vaccine containing whole virus particles purified on a zonal centrifuge is pyrogenic and can cause systemic and local adverse side effects. An improved vaccine was therefore prepared which contained only the surface antigens of the virus adsorbed to aluminium hydroxide.
M I, Brady, I G, Furminger
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Detection of microbial surface antigens that bind Lewisa antigen [PDF]
FEMS Immunology and Medical Microbiology, 1994 There is evidence that the Lewis(a) blood group antigen is one of the receptors for a number of potentially pathogenic microorganisms. To determine how widely distributed the microbial adhesins are that bind this antigen, anti-idiotypic antibodies produced against monoclonal anti-Lewis(a) were used in coagglutination assays to screen a variety of ...
S D, Essery +6 more
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