Results 81 to 90 of about 16,567,586 (308)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Advances in Medical Education and Practice, 2016 Aji Gopakumar,1 Susirith Mendis,2 Jayakumary Muttappallymyalil,3 Jayadevan Sreedharan3 1Department of General Education, 2Continuing Medical Education, Continuing Professional Development and Center for Continuing Education and Community ...
Gopakumar A +3 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Frontiers in EducationThe fast-paced and intricate nature of the current society, coupled with the ongoing changes in educational requirements, calls for the cultivation of higher-order thinking skills.
Ainur Sadykova +5 more
doaj +1 more source
Propenal Hydrogenation on Silver Surface - A Theoretical Approach
Chemical Engineering Transactions, 2013 Catalytic reactions perform best if the interaction between the adsorbates and the surface is not too strong and not too weak. This relates to the d-band occupancy of the metals.
A. Andoni, A. van Santen R
doaj +1 more source
2004 integrated water quality monitoring and assessment report
, 2004 Title from Web page, last updated 21 May 2004 (viewed Dec. 28, 2004).; Harvested from the web on 11/23/05This report indicates the general condition of Ohio's waters and identifies waters that are not meeting water quality goals.This report indicates the
Ohio EPA. Division of Surface Water.
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Aquatic life status, year 2000
, 2000 Title from web page.; Harvested from the web on 2/6 ...
Ohio EPA.Division of Surface Water.
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source