Results 71 to 80 of about 16,567,586 (308)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Experiencia de aula basada en los enfoques de aprendizaje “estudiantes del grado décimo fomentan el desarrollo del espíritu científico en estudiantes de preescolar”

open access: yesRevista Científica, 2012
The experience is based in a practical work oriented by the tenth grade students to a pre-school group in order to introduce them to the world of the experimental sciences.
Manuel Guillermo Soler Contreras   +1 more
doaj  

USING THE CONCEPT OF SURFACE IMPEDANCE IN PROBLEMS OF ELECTRODYNAMICS (75 YEARS LATER)

open access: yesRadio Physics and Radio Astronomy, 2014
An analytical review of literature related to application of the impedance approach in solving electrodynamic boundary value problems for 75 years since 1938, when M. A.
S. L. Berdnik   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Inaccuracy of Surface Landmarks for the Anterior Approach to the Cervical Spine in Southern Chinese Patients [PDF]

open access: yesAsian Spine Journal, 2018
Study Design Observational study. Purpose To assess the correlational accuracy between the traditional anatomic landmarks of the neck and their corresponding vertebral levels in Southern Chinese patients.
Tin Sui Ko   +3 more
doaj   +1 more source

Students' Deep and Surface Approach: Links to Interaction in Learning Environments

open access: yes, 2015
This paper presents the initial results of a study where we embrace and test Entwistle's theory in order to explain the students’ interaction when using interactive learning environments (ILEs) in real conditions.
Margeti, M., Mavrikis, M.
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Validade incremental da Escala de Abordagens de Aprendizagem (EABAP) Incremental validity of the Learning Approaches Scale

open access: yesPsicologia: Reflexão e Crítica, 2012
Este trabalho investiga a validade incremental da abordagem à aprendizagem (AbA) sobre o desempenho escolar, além da inteligência. São analisados dados de 684 estudantes da sexta série ao terceiro ano do ensino médio de uma escola particular de Belo ...
Cristiano Mauro Assis Gomes   +1 more
doaj  

Lie Group Approach to Envelope Surfaces

open access: yesComputer Aided Geometric Design
16 pages (+ references), 9 ...
Molnár, Michal   +2 more
openaire   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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