Results 71 to 80 of about 16,567,586 (308)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The experience is based in a practical work oriented by the tenth grade students to a pre-school group in order to introduce them to the world of the experimental sciences.
Manuel Guillermo Soler Contreras +1 more
doaj
USING THE CONCEPT OF SURFACE IMPEDANCE IN PROBLEMS OF ELECTRODYNAMICS (75 YEARS LATER)
An analytical review of literature related to application of the impedance approach in solving electrodynamic boundary value problems for 75 years since 1938, when M. A.
S. L. Berdnik +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Inaccuracy of Surface Landmarks for the Anterior Approach to the Cervical Spine in Southern Chinese Patients [PDF]
Study Design Observational study. Purpose To assess the correlational accuracy between the traditional anatomic landmarks of the neck and their corresponding vertebral levels in Southern Chinese patients.
Tin Sui Ko +3 more
doaj +1 more source
Students' Deep and Surface Approach: Links to Interaction in Learning Environments
This paper presents the initial results of a study where we embrace and test Entwistle's theory in order to explain the students’ interaction when using interactive learning environments (ILEs) in real conditions.
Margeti, M., Mavrikis, M.
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Este trabalho investiga a validade incremental da abordagem à aprendizagem (AbA) sobre o desempenho escolar, além da inteligência. São analisados dados de 684 estudantes da sexta série ao terceiro ano do ensino médio de uma escola particular de Belo ...
Cristiano Mauro Assis Gomes +1 more
doaj
Lie Group Approach to Envelope Surfaces
16 pages (+ references), 9 ...
Molnár, Michal +2 more
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

