Results 51 to 60 of about 8,294,337 (274)

Performance Simulation of Surface Air Cooler with Bypass Valve

open access: yesProcedia Engineering, 2017
Abstract In this paper, mathematical models of heat exchanger and valve are established according to energy conservation equation and mass conservation equation. MATLAB/Simulink is used as a platform based on the mathematical models to establish simulation model of surface air cooler with bypass valve system including heat exchanger, nonlinear air ...
Zhiqiang Kang   +4 more
openaire   +1 more source

Numerical Study of the Effect of Freestream Turbulence on by-pass Transition in a Boundary Layer [PDF]

open access: yes, 2014
We use direct numerical simulations in the presence of free-stream turbulence having different values of intensity, T u, and integral length scale, L, in order to determine which kind of structures are involved in the path to transition of a boundary ...
Robinet, Jean Christophe   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Investigation of Flexible Surface of (Nellore Bypass) by Falling Weight Deflectometer

open access: yes, 2021
{"references": ["Kumar, R. S. (2014). Pavement Evaluation and Maintenance Management System. Universities Press.", "IRC: 81-1997 Guidelines for Strengthening of Flexible pavement using Bankelman Beam Deflection Technique. (1st Revision)\", Indian Roads Congress, New Delhi", "Pandey, B. B & Reddy K. S.(2003). Research Report on Structural Evaluation
Shivendra Singh Parihar   +3 more
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Risk Factors of Thrombocytopenia After Cardiac Surgery with Cardiopulmonary Bypass

open access: yesBrazilian Journal of Cardiovascular Surgery, 2022
Introduction: Postoperative thrombocytopenia is common in cardiac surgery with cardiopulmonary bypass, and its risk factors are unclear. Methods: This retrospective study enrolled 3,175 adult patients undergoing valve surgeries with cardiopulmonary ...
Shujie Yan   +5 more
doaj   +1 more source

Coagulation, fibrinolysis, and cell activation in patients and shed mediastinal blood during coronary artery bypass grafting with a new heparin-coated surface.

open access: yesJournal of Thoracic and Cardiovascular Surgery, 2002
Objectives: Heparin coating of the cardiopulmonary bypass circuit is shown to improve the biocompatibility of the surface. We have studied a new heparin surface, the Corline Heparin Surface, applied to a complete set of an extracorporeal device used ...
M. Johnell   +5 more
semanticscholar   +2 more sources

Safety and efficacy of heparin-bonded surfaces in cardiopulmonary bypass [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2001
AbstractJ Thorac Cardiovasc Surg 2003;125:S90 ...
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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