Results 51 to 60 of about 6,769,174 (294)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Charge accumulation characteristic on polymer insulator surface under AC voltage in air and C(4)F(7)N/CO(2) mixtures

High Voltage, 2020
Charge accumulation has always been a problem for the safe operation of gas insulated switchgear (GIS)/gas insulated transmission line (GIL) both under AC and DC.
Dayu Li, Guixin Zhang, Guixin Zhang, Tianyu Wang, Yicen Hou   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Gas–solid interface charge characterisation techniques for HVDC GIS/GIL insulators

High Voltage, 2020
Surface charge accumulation on the spacers is one of the key issues restraining the development of HVDC GIS/GIL. The precise measurement of surface charge properties provides the basis for further study of the surface charge transport mechanism as well ...
Lei Zhang, Chuanjie Lin, Chuanyang Li, Simone Vincenzo Suraci, Geng Chen, Uwe Riechert, Uwe Riechert, Tohid Shahsavarian, Masayuki Hikita, Youping Tu, Zhousheng Zhang, Davide Fabiani, Jinliang He, Jinliang He   +13 more
doaj   +1 more source

A simple method considering the synergetic effect of space charge and inhomogeneous material conductivity for DC electric field computation

High Voltage, 2022
The current continuity equation is usually applied to solve DC electric field distribution when there is inhomogeneous material conductivity due to temperature gradient or multi‐layer dielectrics.
Xiao Yang, Yi Zhang, Zhuodong Yang, Hao Dong, Chengrong Li, Bo Qi, Licheng Lu   +6 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Quantifying Electric Charge on Cap-Pin Glass Insulator: Investigating the Impact of Pollution through Simulation and Experimental Approaches

ENP Engineering Science Journal
The objective of this paper is to investigate the behavior of electric charges on cap-pin glass insulator under 50 Hz AC voltage. The study is conducted using COMSOL Multiphysics to understand the charge location, polarity, and parameters affecting their
Rabie Salhi, Abdelouahab Mekhaldi, Madjid Teguar, Omar Kherif   +3 more
doaj   +1 more source

A facile method for producing superhydrophilic glasses via charge injection

AIP Advances, 2018
Superhydrophilic glass has aroused significant interest and attention among researchers because of their excellent performance. A variety of methods by modifying features of the glass such as surface roughness, surface energy, surface chemistry, or ...
Xiangdong Ye, Dongbao Cai, Yuxuan Guo, Junwen Hou   +3 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source