Results 61 to 70 of about 887,698 (266)

HyPyRameter: A Python Toolbox to Calculate Spectral Parameters from Hyperspectral Reflectance Data

The Planetary Science Journal
Hyperspectral image cubes are information rich, typically containing hundreds of wavelengths and millions of spatial pixels. To condense this information into a more interpretable form, it is common to parameterize certain aspects of the spectra that are
Michael S. Phillips, Christian Tai Udovicic, Jeffrey E. Moersch, Udit Basu, Christopher W. Hamilton   +4 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Surface Composition of Asteroid 269 Justitia: Insights from Spectral Mixture Modeling

The Astrophysical Journal
Asteroid (269) Justitia is one of the more unusual asteroids in the main belt due to its extremely red spectral slope at visible and near infrared (VNIR) wavelengths.
Harish, P. O. Hayne, J. P. Emery, W. F. Bottke, Christopher S. Edwards, M. R. El-Maarry, H. AlMazmi, the EMA Science and Space Resources Team   +7 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Visible-infrared Spectra of keV Electron Irradiated Cryogenic Salts with Implications for Europa Surface Composition

The Planetary Science Journal
Visible to near-infrared spectral coloring of cryogenic halides, sulfates, their frozen brines, and sulfuric acid hydrate formed through one to tens of keV electron radiation can inform on the composition of Europa’s surface.
C. A. Hibbitts, K. Stockstill-Cahill, E. Lloyd, E. Gloesener, M. Choukroun, C. Paranicas, R. N. Clark   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Prediction of Sulfate Hazes in the Lower Venus Atmosphere

The Planetary Science Journal
We study the amount, size distribution, and material composition of submicron aerosol particles in the lower Venus atmosphere
Peter Woitke, Manuel Scherf, Christiane Helling, Paul Rimmer, Martin Ferus, Helmut Lammer, Fabian Weichbold, Kateřina Němečková, Petr Eminger, Jaroslav Kačina, Tereza Constantinou   +10 more
doaj   +1 more source