Volatile Elements Characterized by MarSCoDe in Materials at Zhurong Landing Site
The Astronomical JournalThe study of volatile elements on the Martian surface is a critical way to explore the geological evolution history of Mars. Volatile elements such as hydrogen (H), sulfur (S), and chlorine (Cl) on the Martian surface act as proxies for the potential ...
Yizhong Zhang +10 more
doaj +1 more source
Отримання виливків із диференційованими властивостями поверхні
Наукові вісті Національного технічного університету України "Київський політехнічний інститут", 2017 Проблематика. Під час експлуатації литих деталей машин і механізмів найінтенсивнішим зовнішнім впливам піддаються поверхневі шари, тому саме їх структура й властивості визначають працездатність виробів у цілому.
Alexander G. Kovalchuk +2 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Detection of Molecular H2O on Nominally Anhydrous Asteroids
The Planetary Science JournalWe used the FORCAST instrument on SOFIA to obtain mid-infrared spectra (4.9–13.7 μ m) of four S-type asteroids: (7) Iris, (11) Parthenope, (18) Melpomene, and (20) Massalia. Three of these four silicate-rich asteroids (Iris, Melpomene, and Massalia) were
Anicia Arredondo +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Estimate of Water and Hydroxyl Abundance on Asteroid (16) Psyche from JWST Data
The Planetary Science JournalOur understanding of solar system evolution is closely tied to interpretations of asteroid composition, particularly the M-class asteroids. These asteroids were initially thought to be the exposed cores of differentiated planetesimals, a hypothesis based
Stephanie G. Jarmak +12 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
In situ analysis of surface composition and meteorology at the Zhurong landing site on Mars. [PDF]
Natl Sci Rev, 2023 Zhao YS +27 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Modification of the Surface Composition of PTB7-Th: ITIC Blend Using an Additive. [PDF]
Molecules, 2022 Alghamdi AR +4 more
europepmc +1 more source