Results 41 to 50 of about 194,959 (267)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Mechanism exploration of ion-implanted epoxy on surface trap distribution: An approach to augment the vacuum flashover voltages

Nanotechnology Reviews
The augmentation of the epoxy (EP) resin surface to advance flashover performance has become a pivotal point of global interest. This research introduces a novel surface modification method and its mechanism for insulation materials. The research follows
Haq Inzamam Ul, Akram Shakeel, Fang Zhi, Tariq Nazir Muhammad, Al-Ammar Essam A.   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Temperature dependence of Cu:SnO2 film conductivity in air medium

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2023
Temperature conductivity studies of films based on Cu:SnO2 made by magnetron sputtering of the mixed target CuO/SnO2 have been carried out. Temperature conductivity dependencies were substantially nonlinear.
N.A. Klychkov, V.V. Simakov, I.V. Sinev
doaj   +1 more source

Anomalous surface conductivity of Weyl semimetals

Physical Review B, 2022
We calculate the surface dc conductivity of Weyl semimetals and show that it contains an anomalous contribution in addition to a Drude contribution from the Fermi arc. The anomalous part is independent of the surface scattering time, and appears at nonzero temperature and doping (away from the Weyl nodes), increasing quadratically with both with a ...
Hridis K. Pal, Osakpolor Eki Obakpolor, Pavan Hosur   +2 more
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Inverse Conductivity Problem on Riemann Surfaces [PDF]

Journal of Geometric Analysis, 2008
An electrical potential U on a bordered Riemann surface X with conductivity function sigma>0 satisfies equation d(sigma d^cU)=0. The problem of effective reconstruction of sigma is studied. We extend to the case of Riemann surfaces the reconstruction scheme given, firstly, by R.Novikov (1988) for simply connected X. We apply for this new kernels for
Henkin, Gennadi, Michel, Vincent
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Tracking slab surface temperatures with electrical conductivity of glaucophane

Scientific Reports, 2021
Slab surface temperature is one of the key parameters that incur first-order changes in subduction dynamics. However, the current thermal models are based on empirical thermal parameters and do not accurately capture the complex pressure–temperature ...
Geeth Manthilake, Ye Peng, Kenneth T. Koga, Mainak Mookherjee   +3 more
doaj   +1 more source