Results 111 to 120 of about 363,241 (312)

RESIDUAL LIFE PREDICTION AND CRACK GROWTH PROPERTY ANALYSIS FOR NO.17 GORGER COUPLER YOKE WITH SHALLOW SURFACE CRACK

Jixie qiangdu, 2022
In view of the fact that most of the cracks in the coupler yoke are surface cracks with small depth and long length, the shallow surface crack propagation was simulated by FEA method for No.17 forged coupler yoke.
JING ZhiMing, LIU YuJie, ZHANG Juan, KANG GuoZheng   +3 more
doaj  

Line Spring Model and Its Applications to Part-Through Crack Problems in Plates and Shells [PDF]

The line spring model is described and extended to cover the problem of interaction of multiple internal and surface cracks in plates and shells. The shape functions for various related crack geometries obtained from the plane strain solution and the ...
Aksel, B., Erdogan, F.
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Developmental patterns and formation and evolutionary mechanisms of surface cracks induced by the mining of shallowly buried coal seams

Meitian dizhi yu kantan
ObjectiveSurface cracks are recognized as one of the most common geologic hazards in coal mining areas in northern Shaanxi Province. These cracks directly cause damage to surface ecosystems.
Enke HOU, Jiaxin MU, Xiaoshen XIE, Dong FENG, Lei YANG, Yan LI, Tao HE, Kangguang BAO, Xiaosheng CHEN   +8 more
doaj   +1 more source

Finite element analysis of fretting crack propagation

, 2011
In this work, the finite elements method (FEM) is used to analyse the growth of fretting cracks. FEM can be favourably used to extract the stress intensity factors in mixed mode, a typical situation for cracks growing in the vicinity of a fretting ...
Basseville, Stéphanie, Proudhon, Henry
core   +3 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Surface Crack Monitoring by Rayleigh Waves with a Piezoelectric-Polymer-Film Ultrasonic Transducer Array. [PDF]

Sensors (Basel), 2023
Li X, Wong VK, Yousry YM, Lim DBK, Christopher Subhodayam PT, Yao K, Feng L, Qian X, Fan Z.   +8 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Concrete Surface Crack Recognition Based on Coordinate Attention Neural Networks. [PDF]

Comput Intell Neurosci, 2022
Zhang Y, Wang Z.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source