Results 111 to 120 of about 366,784 (310)

Decoding planetary surfaces by counting cracks

Proceedings of the National Academy of Sciences
Planets are often covered with thin cracked shells. From mud films to lithospheres of rock or ice, fracture networks form two-dimensional (2D) tessellations of convex polygons whose geometry encodes their genesis. Here, we chart the geometry of 2D fracture mosaics across the solar system, and decode their formative conditions using a new dynamical ...
S. Silver, K. Regős, D. J. Jerolmack, G. Domokos   +3 more
openaire   +3 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

RESIDUAL LIFE PREDICTION AND CRACK GROWTH PROPERTY ANALYSIS FOR NO.17 GORGER COUPLER YOKE WITH SHALLOW SURFACE CRACK

Jixie qiangdu, 2022
In view of the fact that most of the cracks in the coupler yoke are surface cracks with small depth and long length, the shallow surface crack propagation was simulated by FEA method for No.17 forged coupler yoke.
JING ZhiMing, LIU YuJie, ZHANG Juan, KANG GuoZheng   +3 more
doaj  

A re-evaluation of finite-element models and stress-intensity factors for surface cracks emanating from stress concentrations [PDF]

A re-evaluation of the 3-D finite-element models and methods used to analyze surface crack at stress concentrations is presented. Previous finite-element models used by Raju and Newman for surface and corner cracks at holes were shown to have ill-shaped ...
Newman, J. C., Jr., Raju, I. S., Shivakumar, K. N., Tan, P. W.   +3 more
core   +1 more source

Crack dynamics and crack surfaces in elastic beam lattices

Physical Review E, 1998
The dynamics of propagating cracks is analyzed in elastic two-dimensional lattices of beams. At early times, inertia effects and static stress enhancement combine so that the crack-tip velocity is found to behave as ${t}^{1/7}.$ At late times a minimal crack-tip model reproduces the numerical simulation results. With no disorder and for fast loading, a
Åström, J., Alava, M., Timonen, J.
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Fracture Testing with Surface Crack Specimens [PDF]

Recommendations are given for the design, preparation, and static fracture testing of surface crack specimens. The recommendations are preceded by background information including discussions of stress intensity factors, crack opening displacements, and ...
Orange, T. W.
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Surface Crack Monitoring by Rayleigh Waves with a Piezoelectric-Polymer-Film Ultrasonic Transducer Array. [PDF]

Sensors (Basel), 2023
Li X, Wong VK, Yousry YM, Lim DBK, Christopher Subhodayam PT, Yao K, Feng L, Qian X, Fan Z.   +8 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source