Results 71 to 80 of about 363,241 (312)
Surface crack growth subject to bending and biaxial tension-compression
Fracture and Structural Integrity, 2015 Fatigue surface crack growth and the in-plane and out-of-plane constraint effects are studied through experiments and computations for aluminium alloy D16T.
V. Shlyannikov +3 more
doaj
Shock and Vibration, 2021 Silicon nitride ceramic bearings are widely used for their excellent performance. However, due to their special manufacturing method, cracks will occur on ceramic ball surface, and this initial surface crack will propagate under the action of cyclic ...
Zhe Yuan +5 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Unique fracture surface in fatigue of shot peened maraging steel
Nihon Kikai Gakkai ronbunshuIn order to investigate the effect of microstructure in the surface layer produced by shot peening on fatigue properties of a maraging steel, rotating bending fatigue tests were carried out using shot-peened specimens and electro-polished ones of a 350 ...
Norio KAWAGOISHI +5 more
doaj +1 more source
Fatigue crack surface area and crack front length: new ways to look at fatigue crack growth
MATEC Web of Conferences, 2018 This paper discusses the appropriateness of crack length as a reference dimension for fatigue damage. Current discussion on short crack versus long crack data is still divided between various approaches to model small crack growth.
van Kuijk Jesse +2 more
doaj +1 more source
Decoding planetary surfaces by counting cracks
Proceedings of the National Academy of SciencesPlanets are often covered with thin cracked shells. From mud films to lithospheres of rock or ice, fracture networks form two-dimensional (2D) tessellations of convex polygons whose geometry encodes their genesis. Here, we chart the geometry of 2D fracture mosaics across the solar system, and decode their formative conditions using a new dynamical ...
S. Silver +3 more
openaire +3 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Indentation theory on orthotropic materials subjected to a frictional moving punch
Archives of Mechanics, 2014 The present article establishes a general theory of frictional moving contact of orthotropic materials indented by a moving rigid punch with various punch profiles.
Y.T. Zhou, K.Y. Lee, Y.H. Jang
doaj +1 more source
Correlation between the pivot node concept and fatigue crack closure [PDF]
, 2018 The study of fatigue crack growth has been commonly done by means of bi-dimensional models and assuming a homogeneous behaviour through the thickness. According to the specimen thickness, a state of plane stress or plane strain is presumed.
Camas, Daniel +2 more
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source