Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
River response to late quaternary environmental change in Corsica [PDF]
, 2002 Mediterranean river systems are particularly sensitive to environmental change and often provide good archives to reconstruct fluvial histories. This study investigates river response to environmental change in two steep land river catchments in Corsica.
Hewitt, Suzanne
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Eastern Mediterranean surface water temperatures and d18O composition during deposition of sapropels in the late Quaternary [PDF]
, 2003 Water column stratification increased at climatic transitions from cold to warm periods during the lateQuaternary and led to anoxic conditions and sapropel formation in the deep eastern Mediterranean basins.
Struck, U. +16 more
core +1 more source
Holocene high floods on the Planina Polje, Classical Dinaric Karst, Slovenia
Acta Carsologica, 2012 The Planina Polje is located in the northwestern part of Notranjsko Podolje, Slovenia. Annual floods cover the flattened floor of the polje at elevation 445 m a.s.l. and reach the depth of approximately 8 meters.
Uroš Stepišnik +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Adolescent Dating Violence: How Should Schools Respond? [PDF]
, 2012 Educational leaders have a substantial degree of control over students and generally have a tremendous influence on the decisions that they make. District administrators are already involved in comprehensive efforts to stem sexual harassment, teen ...
Graca, Thomas +3 more
core +1 more source
Marine reservoir variation in the Bismarck region: an evaluation of spatial and temporal change in ∆R and R over the last 3000 years [PDF]
, 2012 Interactions between islands, ocean currents, and winds cause large-scale eddies and upwelling in the lee of islands that can result in spatial variation in the marine radiocarbon reservoir.
Ulm, Sean, Petchey, Fiona
core +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source
Radiocarbon reservoir ages from freshwater lakes, south Georgia, sub-Antarctic: Modern analogues from particulate organic matter and surface sediments [PDF]
, 2004 Lake sediments have the potential to preserve proxy records of past climate change. Organic material suitable for radiocarbon dating often provides age control of such proxy records.
Davies, S.J. +3 more
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