Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Reimagining Material Dating: The Potential Use of ER-FTIR in Cultural Heritage Dating Applications
External reflectance Fourier transform infrared (ER-FTIR) spectroscopy offers a contactless, efficient, and cost-effective method for dating cultural heritage artefacts.
Patrick Layton +10 more
doaj +1 more source
The Paleochrono-1.1 probabilistic model to derive a common age model for several paleoclimatic sites using absolute and relative dating constraints [PDF]
Past climate and environmental changes can be reconstructed using paleoclimate archives such as ice cores, lake and marine sediment cores, speleothems, tree rings, and corals.
F. Parrenin +10 more
doaj +1 more source
A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai +5 more
wiley +1 more source
Groundwater Dating with Noble Gases - from Groundwater-Surface Water Interaction and Contaminant Transport to Paleohydrogeology [PDF]
Groundwater dating provides essential information for an improved understanding of groundwater systems, which, in turn, is crucial for the protection and the sustainable management of groundwater resources.
Gerber, Christoph
core
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Dating Violence, Don\u27t Ignore It! [PDF]
Educational leaders have a substantial degree of control over students and generally have a tremendous influence on the decisions that they make. District administrators are already involved in comprehensive efforts to stem sexual harassment, teen ...
Graca, Thomas +3 more
core +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Le souterrain médiéval de la Croix-Blanche à Sardon (Puy-de-Dôme)
The tunnel at la Croix-Blanche was accidentally discovered by the owner-operator of the plot. A sounding was conducted. It showed the existence of a complex system, presumably linked to storage, comprising a surface silo, an underground room housing two ...
Frédéric Surmely +4 more
doaj
In recent years there has been growing concern all over the globe about marine pollution due to persistent organic pollutants. Sediments, which is an important component of marine environment can serve as sorbent or concentrator for these pollutants.
G.G. Pandit +4 more
doaj +1 more source

