Results 71 to 80 of about 38,626 (306)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Investigation of a cold-based ice apron on a high-mountain permafrost rock wall using ice texture analysis and micro-14C dating: a case study of the Triangle du Tacul ice apron (Mont Blanc massif, France)

Journal of Glaciology, 2021
The current paper studies the dynamics and age of the Triangle du Tacul (TDT) ice apron, a massive ice volume lying on a steep high-mountain rock wall in the French side of the Mont-Blanc massif at an altitude close to 3640 m a.s.l.
Grégoire Guillet, Susanne Preunkert, Ludovic Ravanel, Maurine Montagnat, Ronny Friedrich   +4 more
doaj   +1 more source

Assessment study of lichenometric methods for dating surfaces

Geomorphology, 2007
In this paper, we discuss the advantages and drawbacks of the most classical approaches used in lichenometry. In particular, we perform a detailed comparison among methods based on the statistical analysis of either the largest lichen diameters recorded on geomorphic features or the frequency of all lichens.
Jomelli, Vincent, Grancher, Delphine, Naveau, Philippe, Cooley, Daniel, Brunstein, Daniel   +4 more
openaire   +3 more sources

Lithological controls on light penetration into rock surfaces – Implications for OSL and IRSL surface exposure dating [PDF]

Radiation Measurements, 2018
Luminescence surface exposure dating is a newly developed geochronological technique that allows the age of geological or archaeological rock surfaces to be accurately constrained. This dating method requires measuring and calibrating the depth-dependent luminescence signal below an exposed surface and relies on the assumption that neither the shape of
Meyer, M. C., Gliganic, L. A., Jain, M.; id_orcid 0000-0002-8942-7566, Sohbati, Reza, Schmidmair, D.   +4 more
openaire   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Evaluating post-glacial bedrock erosion and surface exposure duration by coupling in situ optically stimulated luminescence and ¹⁰Be dating [PDF]

, 2019
International audienceAssessing the impact of Quaternary glaciation at the Earth's surface implies an understanding of the long-term evolution of alpine landscapes.
King, Georgina E., Biswas, Rabiul, H, Lehmann, Benjamin, Herman, Frédéric, King, Georgina,, King, Georgina, E, Valla, Pierre, Biswas, Rabiul,, Valla, Pierre G., Biswas, Rabiul H.   +9 more
core   +1 more source

IMD: A Dating Code to Facilitate the Study of Transient Phenomena on the Surface of Mars

Geosciences
Today, we have satellite images of Mars with a resolution of up to 24 cm per pixel. The planet has a thin atmosphere compared to Earth’s, but its surface is revealing itself to be active and complex.
Adriano Nardi, Paolo Bagiacchi, Antonio Piersanti   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Chronologies for Recent Peat Deposits Using Wiggle-matched Radiocarbon Ages: Problems with Old Carbon Contamination [PDF]

, 2005
Dating sediments which have accumulated over the last few hundred years is critical to the calibration of longer-term paleoclimate records with instrumental climate data.
Garnett, M.H., Charman, D.J., Charman, Dan J., Garnett, Mark H.   +3 more
core   +1 more source