Results 71 to 80 of about 1,538,239 (302)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Symmetry Governs Surface Diffusion [PDF]
Physical Review Letters, 2011 In chemistry and physics symmetry principles are all important, for example, leading to the selection rules governing optical transitions. We have investigated the influence of the molecular symmetry on the surface potential landscape of molecules in the limit of weak molecule-substrate binding.
Sonnleitner, Tobias +4 more
openaire +3 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Formation mechanism of porous hollow SnO2 nanofibers prepared by one-step electrospinning
eXPRESS Polymer Letters, 2012 The present study investigates the formation mechanism of hollow SnO2 nanofibers and the form of nanograin growth in nanofibers. SnO2 hollow nanofibers were fabricated by directly annealing electrospun polyvinylpyrrolidone (PVP)/Sn precursor composite ...
Q. F. Wei +4 more
doaj +1 more source
Fluctuations of steps on crystal surfaces
, 2001 Fluctuations of isolated and pairs of ascending steps of monoatomic height are studied in the framework of SOS models, using mainly Monte Carlo techniques.
Bartelt +18 more
core +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Curvature Dependent Diffusion Flow on Surface with Thickness
, 2009 Particle diffusion in a two dimensional curved surface embedded in $R_3$ is considered. In addition to the usual diffusion flow, we find a new flow with an explicit curvature dependence.
H. Meinhardt +3 more
core +1 more source
Error analysis for an ALE evolving surface finite element method [PDF]
, 2014 We consider an arbitrary Lagrangian–Eulerian evolving surface finite element method for the numerical approximation of advection and diffusion of a conserved scalar quantity on a moving surface.
Brenner +20 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source