Results 111 to 120 of about 6,734,388 (302)

Evaluation of a rooftop photovoltaics parameterization in the PALM model system using eddy-covariance observations

Frontiers in Sustainable Cities
The rapid expansion of rooftop photovoltaic (PV) systems in urban areas provides substantial renewable energy capacity while also altering the local urban microclimate through changes in roof radiative properties, surface temperature, and roof-atmosphere
Haoyuan Zhai, Julian Anders, Björn Maronga, Jonathan Lukas Biehl, Stefan Riechelmann, Matthias Mauder   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Constraining ecosystem processes from tower fluxes and atmospheric profiles [PDF]

, 2011
The planetary boundary layer (PBL) provides an important link between the scales and processes resolved by global atmospheric sampling/modeling and site-based flux measurements.
T. C. Hill, Moncrieff, J. B., M. Williams, F. I. Woodward, J. B. Moncrieff, Hill, T. C., Williams, M., Woodward, F. I., Williams, M.; id_orcid   +8 more
core   +1 more source

The rotation–magnetism relationship in solar-type stars

Astronomy & Astrophysics
Context. The rotation–activity relationship of G-type stars results from surface magnetic fields emerging from the interior. How the magnetic flux and its emergence rate scale with rotation rate are not well understood, both observationally and ...
Işık Emre, Solanki Sami K., Krivova Natalie A., Shapiro Alexander I.   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Forced Air‐Cooling of Modular Flux Switching PM Machines Using Flux Gaps as Cooling Channels

IET Electric Power Applications
This paper investigates the thermal performance of modular flux‐switching permanent magnet (FSPM) machines under forced air cooling. Unlike conventional designs with continuous stator iron core, the modular configuration with segmented stator core ...
Guan‐Bo Zhang, Guang‐Jin Li
doaj   +1 more source

Analytical–Numerical Modeling of Transient Heat Flux in a Semi-Infinite Medium Using the Duhamel Integral [PDF]

E3S Web of Conferences
This article integrates the concepts of general analytical solutions (Model 2) based on the Duhamel integral principle in a semi-infinite body model with digital modelling in the Simulink environment (Model 1) for a thermoelectric battery.
Kasimakhunova Anarkhan, Mamarasulov Qudratbek, Nigmatov Ulugbek, Xiaohua Li, Yun Li   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

GEODETIC OBSERVATION AND INTERPRETATION OF ICE FLOW VELOCITIES IN THE SOUTHERN PART OF SUBGLACIAL LAKE VOSTOK

Лëд и снег, 2015
Results of geodetic in-situ observations of ice-flow velocities in the southern part of subglacialLakeVostokare combined with data sets of the ice surface topography, ice thickness, surface accumulation, basal accretion and firn/ice density for ...
A. Richter, D. V. Fedorov, S. V. Popov, M. Fritsche, V. Ya. Lipenkov, A. A. Ekaykin, V. V. Lukin, A. Yu. Matveev, R. Dietrich   +8 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source