Results 61 to 70 of about 16,702 (269)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Self-castellation of tungsten monoblock under high heat flux loading and impact of material properties

open access: yesNuclear Materials and Energy, 2017
In the full-tungsten divertor qualification program at ITER Organization, macro-cracks, so called self-castellation were found in a fraction of tungsten monoblocks during cyclic high heat flux loading at 20MW/m2.
S. Panayotis   +10 more
doaj   +1 more source

Modeled diurnally varying sea surface temperatures and their influence on surface heat fluxes [PDF]

open access: yesJournal of Geophysical Research: Oceans, 2014
AbstractA diurnal warming model is used to create a new data set of global, diurnally varying sea surface temperatures (dSSTs) and surface turbulent heat fluxes over a 5 year period. The magnitude of diurnal warming is primarily a function of low wind speed and net heat flux.
Rachel R. Weihs, Mark. A. Bourassa
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Modelling of Thermal Transient Phenomena in Axial Flux Permanent Magnet Machine Based on Coupling of Two Separeted Models - Electrical and Thermal Models

open access: yesCommunications, 2007
The paper deals with transient thermal modelling of air cooled axial flux permanent magnet machine. It has a rotor with permanent magnets placed on the rotor surface situated between two stators. The simulation model consists of two equivalent circuits -
Eva Belicova
doaj   +1 more source

AN ANALYTICAL MODEL OF HEAT FLUX IN LASER SURFACE TREATMENT

open access: yesLe Journal de Physique Colloques, 1987
A new analytical model of heat flux during laser surface treatment is presented. Prior knowledge of the absorption coefficient is precluded and can be later calculated by giving special consideration to the peak surface temperature which is easily obtained from an optical pyrometer.
Magnin, P., Mayer, H.
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Ion orbit modelling of ELM heat loads on ITER divertor vertical targets

open access: yesNuclear Materials and Energy, 2017
The high heat flux areas on the vertical divertor targets in the ITER tokamak will consist of cuboid tungsten monoblocks bonded to copper cooling tubes. Three-dimensional ion orbit modelling is used to calculate the heating of tungsten monoblocks during ...
J.P. Gunn   +8 more
doaj   +1 more source

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