Results 251 to 260 of about 6,580 (316)

Evaluating Infrared Absorption Parameters for Low-Temperature Ices Using Reflection-Absorption Infrared Spectroscopy. [PDF]

ACS Earth Space Chem
Fulker JE, McCoustra M, Brown WA.
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Methanetetrol and the final frontier in ortho acids. [PDF]

Nat Commun
Marks JH, Bai X, Nikolayev AA, Gong Q, McAnally M, Wang J, Pan Y, Fortenberry RC, Mebel AM, Yang T, Kaiser RI.   +10 more
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

The dynamic Alp landscape of <i>Streptococcus dysgalactiae</i>. [PDF]

Front Cell Infect Microbiol
Olaisen C, Kaci A, Ås CG, Afset JE, Oppegaard O.   +4 more
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Infrared Irradiation of H₂O:CO₂ Ice: A Combined Experimental and Computational Study of the Dissipation of CO₂ Vibrational Excitations. [PDF]

ACS Earth Space Chem
Schrauwen JGM, Dijkhuis TM, Ioppolo S, Galimberti DR, Redlich B, Cuppen HM.   +5 more
europepmc   +1 more source

Adherence to Burn Center Referral Criteria for Pediatric Burns. [PDF]

JAMA Netw Open
Gus E, To T, Fish J, Diong C, Saunders N.   +4 more
europepmc   +1 more source

Pan-immune system, mobilome and resistome in <i>Streptococcus suis</i>. [PDF]

Microb Genom
Dechêne-Tempier M, Bougeard S, Loux V, Chiapello H, Libante V, Marois-Créhan C, Leblond-Bourget N, Payot S.   +7 more
europepmc   +1 more source

Electric Fields Can Assist Prebiotic Reactivity on Hydrogen Cyanide Surfaces. [PDF]

ACS Cent Sci
Cappelletti M, Sandström H, Rahm M.
europepmc   +1 more source