Results 51 to 60 of about 9,504,346 (343)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Surface-wave instability without inertia in shear-thickening suspensions
Communications Physics, 2020 The way interactions at the microscopic scale influence emerging flow properties in complex fluids at the macroscopic scale is one of the core problems in soft matter physics.
Baptiste Darbois Texier +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Instabilities in droplets spreading on gels
, 2007 We report a novel surface-tension driven instability observed for droplets spreading on a compliant substrate. When a droplet is released on the surface of an agar gel, it forms arms/cracks when the ratio of surface tension gradient to gel strength is ...
D. Halpern +5 more
core +1 more source
Growth of surface undulations at the Rosensweig instability [PDF]
, 2007 We investigate the growth of a pattern of liquid crests emerging in a layer of magnetic liquid when subjected to a magnetic field oriented normally to the fluid surface.
Knieling, Holger +4 more
core +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Coexistence of antiferrodistortive and ferroelectric distortions at the PbTiO$_3$ (001) surface
, 2004 The c(2$\times$2) reconstruction of (001) PbTiO$_3$ surfaces is studied by means of first principles calculations for paraelectric (non-polar) and ferroelectric ([001] polarized) films.
A. Munkholm +5 more
core +1 more source
Instabilities and soot formation in spherically expanding, high pressure, rich, iso-octane-air flames [PDF]
, 2006 Flame instabilities, cellular structures and soot formed in high pressure, rich, spherically expanding iso-octane-air flames have been studied experimentally using high speed Schlieren cinematography, OH fluorescence, Mie scattering and laser induced ...
Al-Shahrany A S +6 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Rayleigh-Plateau Dissipative Instability
East European Journal of Physics, 2020 The instability of a freely falling jet of liquid in air taking into account the viscosity of the contacting media is considered. In neglecting the viscosities of both media, instability was studied by Rayleigh and Plateau.
Oksana L. Andreeva +2 more
doaj +1 more source