Results 111 to 120 of about 1,347,538 (354)

Development of a co-cured composite torque shaft for rudder of high speed aircraft [PDF]

, 2008
The Carbon Fibre reinforced Composites are widely used in developing various composite parts of civil and13; military aircraft due to its high specific strength and specific stiffness.
Dharmappa, BL, Karuppannan, D, Rawat, RS, Subba Rao, M   +3 more
core   +1 more source

Expressed in the yeast Saccharomyces cerevisiae, human ERK5 is a client of the Hsp90 chaperone that complements loss of the Slt2p (Mpk1p) cell integrity stress-activated protein kinase [PDF]

, 2006
ERK5 is a mitogen-activated protein (MAP) kinase regulated in human cells by diverse mitogens and stresses but also suspected of mediating the effects of a number of oncogenes.
King, Victoria, Millson, Stefan H, Mollapour, Medhi, Nuttall, James M, Pearl, Laurence H, Piper, Peter W, Prodromou, Chrisostomos, Truman, Andrew W   +7 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Parameter optimization for ultrasonic-assisted grinding of γ-TiAl intermetallics: A gray relational analysis approach with surface integrity evaluation

Reviews on Advanced Materials Science
The processing of γ-TiAl intermetallic compound (Ti–45Al–2Mn–2Nb) is essential for manufacturing aircraft engine components, known for their challenging machinability.
Yang Song, Zhang Guangjin, Xiao Guoqing
doaj   +1 more source

Analysis of Corrosion-Mechanical Properties of Electroplated and Hot-Dip Zinc Coatings on Mechanically Pre-Treated Steel Substrate

Applied Sciences
This study evaluates the effects of three mechanical pre-treatment methods on S235JRG2 steel sheets: blasting with a synthetic corundum (F40), blasting with steel shot (S170), and grinding with synthetic corundum (P40).
Jaroslav Lozrt, Jiří Votava, Vojtěch Kumbár, Adam Polcar   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Effects of cryogenic cooling on the surface integrity in hard turning of AISI D6 steel [PDF]

, 2018
Welber Vasconcelos Leadebal, Anderson Clayton Alves de Melo, Adilson José de Oliveira, Nicolau Apoena Castro   +3 more
openalex   +1 more source

Characterising the impact of surface integrity on the fatigue behaviour of forged components [PDF]

, 2014
The present study focusses on analysing and modelling the influence on fatigue behaviour of the surface of a hot-forged C70 connecting rod which undergoes a shot-blasting treatment.
GERIN, Benjamin, MOREL, Franck, PESSARD, Etienne, VERDU, Catherine   +3 more
core   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source