Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Tool wear monitoring and hole surface quality during CFRP drilling [PDF]
, 2014 The present investigation focuses on the evaluation of tool wear and surface integrity in the context of CFRP cutting. Series of drilling experiments were performed on CFRP plates using cemented carbide solid drills with the aim to investigate ...
RAMIREZ, Christophe +3 more
core +1 more source
Surface integrity analysis when milling ultrafine-grained steels
Materials Research, 2012 This paper quantifies the effects of milling conditions on surface integrity of ultrafine-grained steels. Cutting speed, feed rate and depth of cut were related to microhardness and microstructure of the workpiece beneath machined surface.
Alessandro Roger Rodrigues +7 more
doaj
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Surface Integrity Analysis in Orthogonal Milling of Inconel 718
191196Nickel-based superalloys exhibit excellent corrosion resistance and mechanical strength at elevated temperatures, making them highly sought after for safety-critical applications in the aerospace, nuclear and chemical industries.
Liu, Hui +2 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Surface integrity predictions and optimisation of machining conditions in the turning of AISI H13 tool steel [PDF]
, 2014 Surface integrity (SI) plays a very important role in functional performance. It is dependent on a large number of machining parameters. The major concern of industry is to know which combination of machining parameters provides the best SI of machined ...
OUTEIRO, José +1 more
core
Enhancing surface integrity of additively manufactured inconel 718 by roller burnishing process
, 2022 © 2022 The Author(s).This work presents the effect of burnishing process including burnishing force, burnishing speed and burnishing conditions on surface properties of Inconel 718 alloy fabricated by laser powder based fusion additive manufacturing.
KAYNAK, YUSUF
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Enhancing surface integrity by high-speed extrusion machining
, 2017 High-speed machining (HSM) is an advanced machining technology to form components. However the poor surface integrity tends to appear due to chip flow instability in HSM.
Liu Y +5 more
core +1 more source