Results 81 to 90 of about 5,601,937 (300)

Imaging Material Texture of As-Deposited Selective Laser Melted Parts Using Spatially Resolved Acoustic Spectroscopy

open access: yesApplied Sciences, 2018
Additive manufacturing (AM) is a production technology where material is accumulated to create a structure, often through added shaped layers. The major advantage of additive manufacturing is in creating unique and complex parts for use in areas where ...
Rikesh Patel   +9 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Modeling and experimental research on rough tooth surface contact fatigue calculation considering hardness gradient and residual stress

open access: yesFriction
Surface integrity parameters such as surface topography, hardness gradient, and residual stress have significant impacts on contact fatigue of tooth surface.
Yuqin Wen, Wei Zhou, Jinyuan Tang
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Surface Integrity of Additively Manufactured Workpieces after Machine Hammer Peening

open access: yes
161166Additively manufactured workpieces often exhibit issues such as porosity, roughness, and induced tensile residual stresses. The surface characteristics of such workpieces can be modified by post-processing techniques like Machine Hammer Peening ...
Herrig, Tim   +4 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Surface Integrity and Fatigue Performance of Inconel 718 in Wire Electrical Discharge Machining [PDF]

open access: yes, 2016
This paper presents a study to characterize the surface integrity in wire electrical discharge machining (EDM) of Inconel 718 and investigate its effect on the fatigue performance of the alloy in a four-point bending fatigue mode at room temperature. The
Johansson, Sten,   +8 more
core   +1 more source

ON THE CONCEPT OF SURFACE INTEGRAL [PDF]

open access: yesProceedings of the National Academy of Sciences, 1958
Cesari, L., Turner, L. H.
openaire   +2 more sources

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