Results 81 to 90 of about 5,601,937 (300)
Additive manufacturing (AM) is a production technology where material is accumulated to create a structure, often through added shaped layers. The major advantage of additive manufacturing is in creating unique and complex parts for use in areas where ...
Rikesh Patel +9 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Surface integrity parameters such as surface topography, hardness gradient, and residual stress have significant impacts on contact fatigue of tooth surface.
Yuqin Wen, Wei Zhou, Jinyuan Tang
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Surface Integrity of Additively Manufactured Workpieces after Machine Hammer Peening
161166Additively manufactured workpieces often exhibit issues such as porosity, roughness, and induced tensile residual stresses. The surface characteristics of such workpieces can be modified by post-processing techniques like Machine Hammer Peening ...
Herrig, Tim +4 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Surface Integrity and Fatigue Performance of Inconel 718 in Wire Electrical Discharge Machining [PDF]
This paper presents a study to characterize the surface integrity in wire electrical discharge machining (EDM) of Inconel 718 and investigate its effect on the fatigue performance of the alloy in a four-point bending fatigue mode at room temperature. The
Johansson, Sten, +8 more
core +1 more source
ON THE CONCEPT OF SURFACE INTEGRAL [PDF]
Cesari, L., Turner, L. H.
openaire +2 more sources

