Results 61 to 70 of about 5,601,937 (300)

Grinding effects on surface integrity and mechanical strength of WC-Co cemented carbides [PDF]

open access: yes, 2014
In this study, the correlation existing among grinding, surface integrity, and flexural strength is investigated for WC-Co cemented carbides (hardmetals).
Llanes Pitarch, Luis Miguel   +11 more
core   +1 more source

The Effect of Milling Cooling Conditions on the Surface Integrity and Fatigue Behavior of the GH4169 Superalloy

open access: yesMetals, 2019
The GH4169 superalloy has high strength at high temperatures. Cooling conditions have a major impact on the machined surface integrity, which further affects the fatigue properties of specimens of the GH4169 superalloy.
Rufeng Xu   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Laser Irradiation Effects in Simulated Laser-Assisted Machining of Type 316L SS

open access: yesJournal of Manufacturing and Materials Processing, 2018
Laser surface heating allows for the thermal treating of clearly defined surface areas thanks to the ability to focus the laser beam to a specific point.
Agostino Maurotto   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Effect of Turning and Surface Polishing Treatments on Surface Integrity and Fatigue Performance of Nickel-Based Alloy GH4169

open access: yesMetals, 2018
In this paper, the effects of turning and surface polishing treatments on surface integrity and fatigue properties of superalloy GH4169 were investigated.
Daoxia Wu, Dinghua Zhang, Changfeng Yao
doaj   +1 more source

Study on Surface Integrity and Surface Roughness Model of Titanium Alloy TC21 Milling Considering Tool Vibration

open access: yesApplied Sciences, 2022
Due to its excellent strength, plasticity, and fracture toughness, titanium alloy has been widely used in the aerospace field. The specificity of its application environment places high demands on the surface quality of titanium alloy.
Zhenyu Wang, Hongyu Li, Tianbiao Yu
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Effect of cryogenic cooling and tool wear on surface integrity of turned Ti-6Al-4V [PDF]

open access: yes, 2018
The aim of this work is to investigate the influence of flank wear and cutting fluid (emulsion vs. liquid nitrogen) on surface integrity in turning of titanium alloy Ti-6Al-4V.
Sadik, Ibrahim,   +11 more
core   +1 more source

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