Results 101 to 110 of about 1,319,702 (316)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Aspects of improving the quality of products manufactured by additive technologies

Архитектура, строительство, транспорт
Today, additive technologies are common used in different areas of human life and economics. However, the aspects of technological support for various parameters of accuracy in products obtained with 3D printing are not yet fully understood.
A. I. Starikov, A. S. Gubenko, M. A. Permyakov, V. M. Soloviev, A. A. Tsyganova   +4 more
doaj   +1 more source

Concerning marginal singularities in the boundary-layer flow on a downstream-moving surface

, 1996
The formation of separation singularities in solutions of the classical boundary-layer equations is studied numerically and analytically for the case of a two-dimensional incompressible steady flow near a solid surface moving in the direction of the main
Timoshin, SN
core  

Flow around a cube in a turbulent boundary layer: LES and experiment [PDF]

, 2009
We present a numerical simulation of flow around a surface mounted cube placed in a turbulent boundary layer which, although representing a typical wind environment, has been specifically tailored to match a series of wind tunnel observations.
Thomas, T.G., Lim, Hee Chang, Castro, Ian P.   +2 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Morphological Features and Microstructural Characteristics of Craters on the Surface of Industrial Aluminum Alloy AA6111 Irradiated with a High-Current Pulsed Electron Beam

East European Journal of Physics
Irradiation of the industrial aluminum alloy AA6111 with a high-current pulsed electron beam (HCPEB) with particle energy of 0.35 MeV, a beam current of 2.0 kA, a pulse duration of 5 μs, and a beam diameter of 3 cm results in the formation of a surface ...
V.V. Bryukhovetsky, V.V. Lytvynenko, D.E. Myla, O.L. Rak   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Analysis of the land surface heterogeneity and its impact on atmospheric variables and the aerodynamic and thermodynamic roughness lengths

, 2008
The land surface heterogeneity has a very significant impact on atmospheric variables (air temperature T-a, wind speed u, and humidity q), the aerodynamic roughness length z(0m), thermodynamic roughness length z(0h), and the excess resistance to heat ...
Feddes, R.A., Menenti, M., Ma, Y.M., Wang, J.M.   +3 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Evaluation of the Diurnal Cycle in the Atmospheric Boundary Layer Over Land as Represented by a Variety of Single-Column Models: The Second GABLS Experiment

, 2011
We present the main results from the second model intercomparison within the GEWEX (Global Energy andWater cycle EXperiment) Atmospheric Boundary Layer Study (GABLS).
Bruijn, E.I.F., de, Svensson, G., Angevine, W.M., Holtslag, A.A.M., Steeneveld, G.J., Cheng, A., Mauritsen, T., Beljaars, A., Kumar, V., Bazile, E.   +9 more
core   +1 more source