Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Preliminary characterisation of the surface of cartilage following exposure to saturated and unsaturated synthetic lips [PDF]
Articular cartilage is covered by a microscopic structure known as surface amorphous layer. This surface structure is often the first victim of attack during cartilage degeneration, thereby resulting in a gross impairment in cartilage function such as ...
Gudimetla, Prasad +3 more
core +2 more sources
Modeling sublimation by computer simulation: morphology dependent effective energies
Solid-On-Solid (SOS) computer simulations are employed to investigate the sublimation of surfaces. We distinguish three sublimation regimes: layer-by-layer sublimation, free step flow and hindered step flow.
Aldao +20 more
core +2 more sources
The role of the asymmetric Ekman dissipation term on the energetics of the two-layer quasi-geostrophic model [PDF]
In the two-layer quasi-geostrophic model, the friction between the flow at the lower layer and the surface boundary layer, placed beneath the lower layer, is modeled by the Ekman term, which is a linear dissipation term with respect to the horizontal ...
Gkioulekas, Eleftherios
core +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Characterization of aerosol hygroscopicity, mixing state, and CCN activity at a suburban site in the central North China Plain [PDF]
This study investigates aerosol hygroscopicity, mixing state, and cloud condensation nucleation as part of the Atmosphere–Aerosol–Boundary Layer–Cloud Interaction Joint Experiment performed in the summer of 2016 at Xingtai (XT), a suburban site ...
Y. Wang +15 more
doaj +1 more source
Where surface physics and fluid dynamics meet: rupture of an amphiphile layer by fluid flow
We investigate the fluctuating pattern created by a jet of fluid impingent upon an amphiphile-covered surface. This microscopically thin layer is initially covered with 50 $\mu$m floating particles so that the layer can be visualized.
Frisch U. +6 more
core +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Optimized Estimation of Surface Layer Characteristics from Profiling Measurements
New sampling techniques such as tethered-balloon-based measurements or small unmanned aerial vehicles are capable of providing multiple profiles of the Marine Atmospheric Surface Layer (MASL) in a short time period.
Doreene Kang, Qing Wang
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

