Results 61 to 70 of about 1,319,702 (316)

Direct numerical simulation of unsheared turbulence diffusing toward a free-slip or no-slip surface [PDF]

open access: yes, 2010
The physics involved in the interaction between statistically steady, shearless turbulence and a blocking surface is investigated with the aid of direct numerical simulation. The original conguration introduced by Campagne et al.
Bodart, Julien   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Observation of Surface Layering in a Nonmetallic Liquid [PDF]

open access: yesPhysical Review Letters, 2006
accepted for publication in Phys. Rev. Lett.
Mo, Haiding   +5 more
openaire   +3 more sources

Supporting data for: Numerical Study of Near-Surface Jet in the Atmospheric Surface Layer over Oceanic Fronts

open access: yes, 2020
Simulation data used for figures in "Numerical study of near-surface jet in the atmospheric surface layer over oceanic fronts" including the mean velocity profiles, the turbulent variance profiles, the vortex structures, the streamwise momentum flux, the
Shen, Lian   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Surfaces with occlusions from layered stereo [PDF]

open access: yes2003 IEEE Computer Society Conference on Computer Vision and Pattern Recognition, 2003. Proceedings., 2003
We propose a new binocular stereo algorithm that estimates scene structure as a collection of smooth surface patches. The disparities within each patch are modeled by a continuous-valued spline, while the extent of each patch is represented via a pixelwise partitioning of the images.
Michael H. Lin, Carlo Tomasi
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Instabilities in a high-Reynolds-number boundary layer on a film-coated surface [PDF]

open access: yes, 1997
A high-Reynolds-number asymptotic theory is developed for linear instability waves in a two-dimensional incompressible boundary layer on a flat surface coated with a thin film of a different fluid.
Timoshin, SN
core  

The effect of Surface Heterogeneity on the Temperature-Humidity Correlation and the Relative Transport Efficiency

open access: yes, 2008
We derive a conceptual model of the flow over heterogeneous terrain consisting of patches with contrasting Bowen ratios. Upward moving eddies are assumed to carry heterogeneous properties, whereas downward moving eddies carry homogeneous properties. This
Dirk Schüttemeyer   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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