Results 31 to 40 of about 6,394,012 (262)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Cold Plasma Treatment of PET Fabrics: AFM Surface Morphology Characterisation

open access: yes, 2003
Atomic force microscopy (AFM) has been used to investigate the morphology changes in the surface of poly((ethyleneterephthalate) (PET) fabrics due to cold plasma treatments.
F. Orsini   +4 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

First principles investigation of the surface stability and equilibrium morphology of MoO3

open access: yes, 2019
The surface stability and equilibrium morphology of MoO 3 were investigated by the first principles calculations. The thermodynamic energies of the stoichiometric surfaces of MoO 3 are in the order (0 1 0) < (1 0 1) < (0 0 1) < (1 0 0).
Jiang, Y   +7 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Surface structure and morphology of InAs(111)B with/without gold nanoparticles annealed under arsenic or atomic hydrogen flux

open access: yes, 2010
We have investigated the structure and morphology of the InAs(1 1 1)B surface using Low Energy Electron Diffraction (LEED), Scanning Tunneling Microscopy (STM) and Scanning Electron Microscopy (SEM).
Lundgren, Edvin   +9 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Surface morphology of four points under spindle speed 3000 r/min.

open access: yes, 2023
(a) Surface morphology of point a. (b) Surface morphology of point b. (c) Surface morphology of point c. (d) Surface morphology of point d.
Yonggou Lou (13184178)   +3 more
core   +1 more source

Surface Morphologies of Chemically Treated Hydroxyapatite [PDF]

open access: yesJournal of Dental Research, 1979
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/66680/2/10.1177_00220345790580060301 ...
Fan, P. L.   +2 more
openaire   +3 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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