Results 201 to 210 of about 5,652,788 (287)

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

Advanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan, Xinzhe Feng, Chuanju Liu, Jianfei Tong, Zhi Li, Chenxu Liu, Yutong Dong, Chen Meng, Yihong Xu, Weidong Xu   +9 more
wiley   +1 more source

Surface Plasmon Resonance Imaging for Gas Sensing

Measurement + Control, 1997
J.N. Wilde, M.C. Petty, J. Saffell, A. Tempore, L. Valli   +4 more
doaj   +1 more source

Accessing real-time interaction between antimicrobial liposomes and live <i>Staphylococcus epidermidis</i> using surface plasmon resonance microscopy. [PDF]

Biosens Bioelectron X
Chan KH, Batista ND, Diego-Perez K, Garcia A, Soriano R, Kala M, Cazares JL, Belleca S, Ao S, Dhoj C, Dai Z, Ho SO, Fujii G, Porter E, Wang Y.   +14 more
europepmc   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Surface Plasmon Resonance Sensors Based on the Molecularly Imprinted Technique for Simvastatin Detection. [PDF]

ACS Omega
Faalnouri S, Çimen D, Denizli A, Bereli N.   +3 more
europepmc   +1 more source

Mitochondrial Localization of Cx26 Promotes Colorectal Cancer Malignancy and Exposes a Fatal Vulnerability to Drug Targeting

Advanced Science, EarlyView.
Mitochondrial localization of Cx26 emerges as a double‐edged sword in colorectal cancer. PIMT‐mediated methylation of Cx26 promotes its mitochondrial localization and stability. Mitochondrial Cx26 then facilitates ER‐mitochondria communication and Ca2+ signaling, thereby promoting metastatic progression. Bortezomib exploits this malignant adaptation by
Jie Wang, Lu Chen, Jia Qin, Xiaoning Wang, Sunlan Ye, Ning An, Mei Bai, Yan Shen, Xuefeng Wu, Qiang Xu   +9 more
wiley   +1 more source

Experimental Determination of the Dielectric Constant of Micellar Hydration Layer via Localized Surface Plasmon Resonance of Gold Nanoparticles. [PDF]

Eur Phys J E Soft Matter
Patel EJ, Carneiro JLM, Turchiello RF, Gómez SL.   +3 more
europepmc   +1 more source

Modifying Electrochemical Doping in Light‐Emitting Electrochemical Cells With Gold Nanoparticles

Advanced Science, EarlyView.
This study shows that gold nanoparticles placed at an electrode can control how electrochemical doping occurs in organic electronic devices. Particularly, in light‐emitting electrochemical cells, by shifting the light‐emitting region, device efficiency is improved without altering the emissive material. This approach provides a simple and effective way
Ajay K. Poonia, Anton Kirch, Joan Ràfols‐Ribé, Lucrezia Catanzaro, Anish Rao, Karol Kołątaj, Vittorio Scardaci, Giuseppe Compagnini, Guillermo P. Acuna, Ludvig Edman, Nicolò Maccaferri   +10 more
wiley   +1 more source

The Development of Foodborne Pathogen Detection and Biosensor Design for Surface Plasmon Resonance Technology. [PDF]

Biosensors (Basel)
Hu Y, Yang J, Chen J, Sun X, Hu W, Liu X.   +5 more
europepmc   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source