Results 221 to 230 of about 88,611 (307)

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source

High-Sensitivity MXene-Functionalized Photonic Crystal Fiber Surface Plasmon Resonance Sensor with Dual Rectangular Grooves for Cancer Detection. [PDF]

Sensors (Basel)
Lu M, He Y, Xi S, Zhong P, Zhang Y, Tian H, Wang Y, Lu H, Hu J, Tang J.   +9 more
europepmc   +1 more source

In Situ Metallic Bi-Modified (110)BiOBr Nanosheets with Surface Plasmon Resonance Effect for Enhancing Photocatalytic Performance Despite of Larger Optical Band Gap [PDF]

Yunhe Mu, Hongxue Chu, Hougang Fan, Xin Li, Xiaoyan Liu, Lili Yang, Maobin Wei, Huilian Liu   +7 more
openalex   +1 more source

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen, Aleksandr Barulin, Won Jong Yu, Jong‐Chan Park, Inki Kim   +4 more
wiley   +1 more source

Peptide Nucleic Acid Probes for MicroRNA Detection: Mg²⁺ Ion Effect, Surface Hybridization, and Surface Plasmon Resonance Biosensing. [PDF]

ACS Meas Sci Au
Jungbluth V, D'Agata R, Bellassai N, Volpi S, Corradini R, Spoto G.   +5 more
europepmc   +1 more source

1P112 Analysis of calmodulin binding to nNOS isoforms using surface plasmon resonance(Heme proteins,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Kaori Azuma, Masayuki Oda, Sumio Ishijima, Ikuko Sagami   +3 more
openalex   +2 more sources

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

Advanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu, Xuechun Yu, Yanling Li, Lin An, Rongrong Zhang, Rong Zhang, Fan Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

Identification of the Mechanisms of a Localized Surface Plasmon Resonance Peak Blue Shift in Magnetic Field Pretreated ZnO/Ag Nanocomposites. [PDF]

ACS Omega
Redko R, Shvalagin V, Milenin G, Redko S, Sarikov A.   +4 more
europepmc   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

A Surface Plasmon Resonance-Based Integrated Assay for Quantification and Glycosylation Characterization of Monoclonal Antibodies in Crude Heterogeneous Samples. [PDF]

Biotechnol Bioeng
Metayer I, Forest-Nault C, Guimond J, Joubert S, Henry O, Durocher Y, De Crescenzo G, Gaudreault J.   +7 more
europepmc   +1 more source