Results 161 to 170 of about 118,586 (322)

Bio‐Based Microfluidics With Snail Slime: A By‐Product of Agriculture Plays an Exciting Role in the Chemistry of Microfluidic Reaction Chambers

Macromolecular Rapid Communications, EarlyView.
Due to a broad spectrum of active ingredients, snail slime presents a variety of exciting physical properties and chemical reactivities. Especially in the role of the reduction‐ and stabilizing agent for the manufacturing of gold nanoparticles, its great potential is revealed. Utilising the proteins found in slime, Nanoparticle‐comprising hydrogels are
Andrea Koball, Jens Gaitzsch
wiley   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

The Race to Salvage Glucocerebrosidase: Understanding Small‐Molecule Therapies for GBA1‐Associated Parkinsonism

Movement Disorders, EarlyView.
Variants in GBA1, the gene encoding the lysosomal enzyme glucocerebrosidase, cause Gaucher disease and confer an increased risk for parkinsonism. Strategies using small molecules can improve the function of glucocerebrosidase in lysosomes. A clear understanding of the mechanism‐of‐action of these compounds will facilitate development of GBA1‐modulating
Mark J. Henderson, Tiffany C. Chen, Logan M. Glasstetter, Yu Chen, Juan J. Marugan, Ellen Sidransky   +5 more
wiley   +1 more source

Quantitative Detection of <i>Salmonella Typhimurium</i> in Ground Chicken Using a Surface Plasmon Resonance (SPR) Biosensor. [PDF]

Biosensors (Basel)
Thapa S, Chen FC.
europepmc   +1 more source

Spinel Aluminate‐Based Heterojunctions as Photocatalyst: A Review

ChemistryOpen, EarlyView.
Spinel aluminates (MAl2O4; M = Zn, Mg, Ca, Sr) serve as robust platforms for designing heterojunction photocatalysts. Their stable lattices, tunable band structures, and efficient charge transport enable improved light‐driven carrier separation, significantly enhancing pollutant degradation efficiency in advanced photocatalytic systems.
Ancy Kurian, Sumathi Shanmugam
wiley   +1 more source

Surface Plasmon Resonance (SPR)-Based Workflow for High-Throughput Discovery of CD28-Targeted Small Molecules. [PDF]

ACS Omega
Calvo-Barreiro L, Nada H, Upadhyay S, Gabr MT.   +3 more
europepmc   +1 more source

Investigation of Surface Plasmon Resonance (SPR) in MoS₂- and WS₂-Protected Titanium Side-Polished Optical Fiber as a Humidity Sensor. [PDF]

Micromachines (Basel), 2019
Zakaria R, Zainuddin NAM, Leong TC, Rosli R, Rusdi MF, Harun SW, Sadegh Amiri I.   +6 more
europepmc   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Surface Plasmon Resonance (SPR) for the Binding Kinetics Analysis of Synthetic Cannabinoids: Advancing CB1 Receptor Interaction Studies. [PDF]

Int J Mol Sci
Shi X, Kuai L, Xu D, Qiao Y, Chen Y, Di B, Xu P.   +6 more
europepmc   +1 more source

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

Phytotherapy Research, EarlyView.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao, Tao Xu, Chao Ye, Ke Zhang, Xinyu Heng, Shaohong Huang, Yan Chen, Yitong Guo, Shengyi Shao, Zhi Wen, Chenwen Shao, Xiang Lu, Ning Sun, Hai Yang   +13 more
wiley   +1 more source