Results 121 to 130 of about 2,581,564 (248)
Tooth profile analysiis of circular-cut, spiral-bevel gears [PDF]
An analysis of tooth profile changes in the transverse plane of circular-cut, spiral-bevel crown gears is presented. The analysis assumes a straight-line profile in the mid-transverse plane.
Coy, J. J., Huston, R. L., Lin, Y.
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Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Analysis of Influence of Tool Installation Error on the Tooth Profile Surface of Face Gear
Jixie chuandong, 2019 In order to analyze the influence of the tool installation error on the tooth profile surface of the face gear,the meshing coordinate system of the face gear machining with the tool installation error is established. The tooth profile surface equation of
Li Xiaozhen +2 more
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Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
On the profile characteristics of technical surfaces as applied to nanoroughness
Физико-химические аспекты изучения кластеров, наноструктур и наноматериаловThe parameters of the structure of a technical surface at the nanoscale level, determined by the profile method, are considered. The possibility of applying the parameters determined in accordance with domestic and international standards for the ...
V.V. Izmailov, M.V. Novoselova
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FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Surface Profile Height Measurement Using Optical Interferometry Method [PDF]
Interferometer is one of the methods that are used for measuring surface profile with high accuracy reach to the order of 1/1000 of the wavelength of the light.
Jiang, Xiang +2 more
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