Results 101 to 110 of about 10,971,821 (293)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
In the present research biocomposites based on extracts of collagen and keratin recovered from the leather industry by-products were made and the specific properties for applications in agriculture and industry were studied.
Niculescu Mihaela-Doina +5 more
doaj +1 more source
Plasma nitriding of the inner surface of stainless steel tubes
Publisher Copyright: © 2018 Elsevier B.V.Stainless steels, especially the austenitic grades, present a good corrosion resistance but poor mechanical properties.
Ibáñez, Iñigo +13 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
2004 integrated water quality monitoring and assessment report
Title from Web page, last updated 21 May 2004 (viewed Dec. 28, 2004).; Harvested from the web on 11/23/05This report indicates the general condition of Ohio's waters and identifies waters that are not meeting water quality goals.This report indicates the
Ohio EPA. Division of Surface Water.
core
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Hydrophobization of Cold Plasma Activated Glass Surfaces by Hexamethyldisilazane Treatment
The objective of this study was to investigate the modification of glass surfaces by the synergistic combination of cold plasma and chemical surface modification techniques.
Konrad Terpiłowski +6 more
doaj +1 more source
Surface properties of alkaline earth metal oxides
Structural and energetic surface properties of the alkaline earth metal oxides MgO, CaO, SrO, and BaO are investigated within the density functional theory.
Broqvist, Peter +6 more
core +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source

