Results 91 to 100 of about 5,120,113 (294)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Comparison of Surface Roughness of Class V Cavity Preparation using Diamond Abrasive Point and Ultrasonic Tip and Measurement of Shear Bond Strength after Restoration with Composite Resin: An In-vitro Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Non Carious Cervical Lesions (NCCLs) represent a prevalent dental condition characterised by the erosion of tooth structure at the cementoenamel junction without the involvement of dental caries.
Abhijit Ghosh, Priti D Desai, Ipsita Maity, Paromita Mazumdar   +3 more
doaj   +1 more source

Simulation of fluid flow in hydrophobic rough microchannels

, 2008
Surface effects become important in microfluidic setups because the surface to volume ratio becomes large. In such setups the surface roughness is not any longer small compared to the length scale of the system and the wetting properties of the wall have
Christian Kunert, Jens Harting, Landau L., Navier C., Schlichting H., Succi S.   +5 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A Property that Characterizes the Enneper Surface and Helix Surfaces

Mediterranean Journal of Mathematics
AbstractThe main goal of this paper is to show that helix surfaces and the Enneper surface are the only surfaces in the 3-dimensional Euclidean space $$\mathbb {R}^{3}$$ R 3 whose isogonal lines are generalized ...
Lucas, Pascual, Ortega-Yagües, José Antonio   +1 more
openaire   +3 more sources

Polarimetry of transneptunian objects (136472) Makemake and (90482) Orcus

, 2012
Context. We study the surface properties of transneptunian populations of Solar-system bodies. Aims. We investigate the surface characteristics of the dwarf planet (136472) Makemake and the resonant object (90482) Orcus. Methods.
Bagnulo, S., Barucci, M. A., Belskaya, I. N., Fornasier, S., Muinonen, K., Shkuratov, Yu. G., Stinson, A., Tozzi, G. P.   +7 more
core   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Synthesis and Properties of Novel Acrylic Fluorinated Surfactants

Surfaces
Branched fluorinated surfactants with creatively introduced acrylate in the hydrophilic group were designed and prepared by adopting perfluoro-2-methyl-2-pentene as the raw substrate.
Chao Lin, Jinhua Li, Yejun Qin, Ping Xing, Biao Jiang   +4 more
doaj   +1 more source

Rough surface scattering in many-mode conducting channels: Gradient versus amplitude scattering

, 2004
We study the effect of surface scattering on transport properties in many-mode conducting channels (electron waveguides). Assuming a strong roughness of the surface profiles, we show that there are two independent control parameters that determine ...
García-Martín, García-Martín, Izrailev, Izrailev, Leadbeater, Luna-Acosta, Makarov, Sánchez-Gil   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source