Results 71 to 80 of about 10,971,821 (293)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Improved Thermal Stability and Wettability Behavior of Thermoplastic Polyurethane / Barium Metaborate Composites [PDF]

Materials Research, 2016
In this paper, it was targeted to the enhance thermal stability and wettability behavior of thermoplastic polyurethane (TPU) by adding barium metaborate. TPU-Barium metaborate composites were prepared by adding various proportions of barium metaborate to
Emre Baştürk, Seyfullah Madakbaş, Memet Vezir Kahraman   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Mechanochemical Synthesis and Characterization of CuInS2/ZnS Nanocrystals

Molecules, 2019
In this study, CuInS2/ZnS nanocrystals were synthesized by a two-step mechanochemical synthesis for the first time. In the first step, tetragonal CuInS2 was prepared from copper, indium and sulphur precursors.
Erika Dutková, Nina Daneu, Zdenka Lukáčová Bujňáková, Matej Baláž, Jaroslav Kováč, Jaroslav Kováč, Peter Baláž   +6 more
doaj   +1 more source

Synthesis and properties of lipoamino acid/fatty acid mixtures. Influence of the amphiphilic structure. [PDF]

, 2009
The acylation of amino acids by acid chlorides with from 8 to 12 carbon atoms, in alkaline aqueous medium following Shotten-Baumann reaction, results in sodium salts of Nα-acylamino acids and fatty acids mixture. These lastest are present in proportion
Jean‐François Blanco, Blanco, J.-F., Rondel, Caroline, Mouloungui, Zephirin,, Blanco, Jean-François, Isabelle Alric, Mouloungui, Zéphirin, Zéphirin Mouloungui, Mouloungui, Zephirin, Z., Françoise Silvestre, Alric, Isabelle, Caroline Rondel, Silvestre, Françoise, Rondel, C.   +13 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Surface properties of electronic materials /

, 1988
The Chemical Physics of Solid Surfaces and Heterogeneous Catalysis.Includes bibliographical references and index.Print version record.Front Cover; Surface Properties of Electronic Materials; Copyright Page; Preface; Table of Contents; Chapter 1.
King, D. A.(David Anthony),, Woodruff, D. P.   +1 more
core  

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source