Results 131 to 140 of about 4,007,124 (352)

The Choice of Optimal Cutting Conditions, Taking into Account the Quality of the Machined Surface of the Part on the Roland MDX20 Milling Machine

open access: yesRUDN Journal of Engineering Research
The results of optimizing the milling process on the Roland MDX-20 machine are presented: the maximum allowable and optimal cutting conditions for parts made of foam, hard and soft modeling plastics, and hardwood are empirically established. At the first
Dmitry G. Allenov   +4 more
doaj   +1 more source

Effects of etchant stirring on the surface quality of the metallography sample [PDF]

open access: diamond, 2023
Ondřej Ambrož   +3 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Experimental Study on Dispersion Stability and Polishing Performance of Polishing Solution Based on Micro-Abrasive Water Jet Polishing

open access: yesApplied Sciences
In micro-abrasive water jet polishing (MAWJP) technology, where abrasive particles serve as polishing tools, particles tend to form large clusters, leading to increased nozzle wear and diminished material polishing quality. Achieving a polishing solution
Lin Lin   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Wood machining properties of Australian plantation-grown Eucalypts

open access: yesMaderas: Ciencia y Tecnología, 2016
This study assessed the moulding, drilling, turning, sanding, and routing properties of seven plantation-grown hardwood species from southeast Australia to evaluate their potential as a resource for the manufacture of high quality furniture and ...
Benoit Belleville   +2 more
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Effect of Nanographene Water-Based Lubricant (NGWL) on Removal Behavior of Pure Copper

open access: yesLubricants
Pure copper is an important metal material in the fields of integrated circuits, mold manufacturing, and aerospace. Its excellent ductility and plasticity lead to problems such as burrs and tool wear in cutting, which poses great challenges to the ...
Ziheng Wang   +7 more
doaj   +1 more source

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