Results 41 to 50 of about 4,025,166 (302)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

The effect of injection process for microcellular foaming on the cell morphology and surface quality of Polyamide 6

open access: yesMaterials Research Express, 2021
Microcellular foamed polymers have been widely used in the traffic field. However, it is difficult to successfully manufacture microcellular foamed products that simultaneously possess good cell morphology, small size, high cell density, and great ...
Tuanhui Jiang   +5 more
doaj   +1 more source

Decreasing groundwater quality at Cisadane riverbanks: groundwater-surface water approach

open access: yes, 2016
The decreasing of groundwater quality has been the major issue in Tangerang area. One of the key process is the interaction between groundwater and Cisadane river water, which flows over volcanic deposits of Bojongmanik Fm, Genteng Fm, Tuf Banten, and ...
Irawan, Dasapta Erwin   +4 more
core   +2 more sources

Fabrication and characterizations of proton-exchanged LiNbO3 waveguides fabricated by inductively coupled plasma technique [PDF]

open access: yes, 2006
This Letter reports the use of an inductively coupled plasma technique for fabrication of proton-exchanged (PE) LiNbO3 (LN) waveguides. Planar and stripe waveguides have been formed in Y-cut LN which are difficult to obtain with the conventional molten ...
Hallam, K. R.   +6 more
core   +1 more source

Surface quality and surface waves on subwavelength-structured silver films [PDF]

open access: yesPhysical Review E, 2007
We analyze the physical-chemical surface properties of single-slit, single-groove subwavelength-structured silver films with high-resolution transmission electron microscopy and calculate exact solutions to Maxwell's equations corresponding to recent far-field interferometry experiments using these structures.
Gay, G.   +6 more
openaire   +4 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Effect of additive and subtractive hybrid manufacturing process on the surface quality of 18Ni300 maraging steel

open access: yesMaterials Research Express, 2023
The effect of process parameters on the surface quality of 18Ni300 maraging steel formed by selective laser melting (SLM) was investigated. Surface modification of SLM specimens was performed using milling as a subtraction method to investigate the ...
Qixian Guo, Yanshuang Wang, Jianghai Lin
doaj   +1 more source

Optimization of cut surface quality during CNC Plasma Arc Cutting process [PDF]

open access: yes, 2016
Optimization of cut surface quality during CNC plasma-arc cutting (PAC) of mild steel plates is presented. Using design of experiments (DOE) the optimum process parameters are estimated.
Kechagias, John   +3 more
core  

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

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