Realization of High Efficiency and Low Damage Machining of Anisotropic KDP Crystal by Grinding [PDF]
, 2019 Potassium dihydrogen phosphate (KDP) is a non-linear material used in various opto-electronic applications including Q-switches, high-speed photography shutters, frequency harmonic generation lens and Pockels cells in the Inertial Confinement Fusion (ICF)
Cai, Rui +4 more
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Engineering ProceedingsThe study begins with a comprehensive experimental investigation into the cutting capability of SS 431 steel using abrasive water jet machining (AWJM), focusing on optimizing the process through a response surface methodology (RSM-BBD) approach ...
Balasubramaniyan Chandrasekaran +5 more
doaj +1 more source
Impact of mining activities in the Upper Silesian Coal Basin on surface water and possibilities of its reduction [PDF]
, 2015 Due to the deposits of quality hard coal, the area of the Upper Silesian Coal Basin (USCB) has been one of the most industrialised regions in Europe for centuries.
Adamczyk, Zdzisław +3 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
MicromachinesEnhancing the operational efficacy of electrical discharge machining (EDM) is crucial for achieving optimal results in various engineering materials. This study introduces an innovative solution—the use of coated electrodes—representing a significant ...
Hoang-Vuong Pham +4 more
doaj +1 more source
National Ambient Water Quality Criteria.................................................................... 7-9 Agricultural Water Quality Limits................................................................................. 7-9 [PDF]
US Geological Survey (USGS)........................................................................................
Surface Water Quality
core
Density and $T_1$ of surface and bulk spins in diamond in high magnetic field gradients [PDF]
, 2018 We report on surface and bulk spin density measurements of diamond, using ultra-sensitive magnetic force microscopy with magnetic field gradients up to 0.5 T/$\mu$m.
de Voogd, Marc +3 more
core +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source