Results 71 to 80 of about 3,984,716 (355)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Determination of Optimal Machining Parameters Based on Roughness and Vibration Measurements of Pieces Produced by Whirling on a Lathe Machine

Machines
Worms can be produced using special machines or standard lathes equipped with a whirling thread-cutting device. A blank is placed on the mandrel and tightened using the three-jawed chuck of the standard lathe.
Zlatko Botak, Katarina Pisačić, Marko Horvat, Tanja Tomić   +3 more
doaj   +1 more source

Microstructure and Surface Roughness Connection on Machined Ductile Iron: An Experimental Determination [PDF]

E3S Web of Conferences
Ductile iron is useful for a variety of engineering challenges because of its ductility and high strength. Hence, it is an excellent option if machining is required. After milling operations, however, various surface characteristics could be created, and
Teke Ibrahim T., Oktay Mehmet, Baykara Celalettin, Ertas Ahmet H.   +3 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Generating High-Quality Surface Realizations Using Data Augmentation and Factored Sequence Models

, 2018
This work presents a new state of the art in reconstruction of surface realizations from obfuscated text. We identify the lack of sufficient training data as the major obstacle to training high-performing models, and solve this issue by generating large ...
Elder, Henry, Hokamp, Chris
core   +1 more source

Realization of High Efficiency and Low Damage Machining of Anisotropic KDP Crystal by Grinding [PDF]

, 2019
Potassium dihydrogen phosphate (KDP) is a non-linear material used in various opto-electronic applications including Q-switches, high-speed photography shutters, frequency harmonic generation lens and Pockels cells in the Inertial Confinement Fusion (ICF)
Cai, Rui, Jin, Tan, Lu, Ange, Qu, Meina, Xie, Guizhi   +4 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Improved surface quality of anisotropically etched silicon {111} planes for mm-scale integrated optics

, 2013
We have studied the surface quality of millimeter-scale optical mirrors produced by etching CZ and FZ silicon wafers in potassium hydroxide to expose the $\{111\}$ planes.
Cotter, J. P., Hinds, E A, Kraft, M, Zeimpekis, I.   +3 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

National Ambient Water Quality Criteria.................................................................... 7-9 Agricultural Water Quality Limits................................................................................. 7-9 [PDF]

US Geological Survey (USGS)........................................................................................
Surface Water Quality
core