Results 81 to 90 of about 12,066,747 (304)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Procedures to Implement the Texas Surface Water Quality Standards [PDF]

, 2003
This document explains procedures the Texas Natural Resource Conservation Commission (TNRCC) uses when applying the water quality standards to wastewater discharge permits issued under the Texas Pollutant Discharge Elimination System (TPDES)
Texas Commission on Environmental Quality. Water Quality Division.
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Experimental Evidence on Incremental Formed Polymer Sheets Using a Stair Toolpath Strategy

Journal of Manufacturing and Materials Processing
Incremental sheet forming represents a relatively recent technology, similar to the layered manufacturing principle of the rapid prototype approach; it is very suitable for small series production and guarantees cost-effectiveness because it does not ...
Antonio Formisano, Luca Boccarusso, Dario De Fazio, Massimo Durante   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

2004 integrated water quality monitoring and assessment report

, 2004
Title from Web page, last updated 21 May 2004 (viewed Dec. 28, 2004).; Harvested from the web on 11/23/05This report indicates the general condition of Ohio's waters and identifies waters that are not meeting water quality goals.This report indicates the
Ohio EPA. Division of Surface Water.
core  

Drillability of Titanium Alloy 6246 from Surface Quality Perspective

, 2019
Drillablity derived from term of machinability, which is applied in drilling. In this study, drillability of titanium alloy 6246 has been investigated through observation of two responses of drilled holes quality, i.e.
Darsin, M, Pasang, T
core   +1 more source

Evaluation of Peripheral Milling and Abrasive Water Jet Cutting in CFRP Manufacturing: Analysis of Defects and Surface Quality

Fibers
The use of carbon fiber reinforced polymers (CFRP) is crucial in industries, such as aerospace, automotive, and marine, due to their excellent strength-to-weight ratio and corrosion resistance.
Alejandro Sambruno, Álvaro Gómez-Parra, Pablo Márquez, Iñaki Tellaeche-Herrera, Moisés Batista   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Supramolecular structure of polymers and its effect on surface quality of injection molded parts using various surface quality of cavities [PDF]

, 2016
This article is focused on influence of finishing operations on the surface quality of polymer products. Finishing operations are the necessary part in the production of injection mold cavities.
Bílek, Ondřej, Pata, Vladimír, Ondřej Bílek, Ladislav Fojtl, Čop, Jiří, Vladimír Pata, Jiří Čop, Fojtl, Ladislav   +7 more
core   +2 more sources