Results 71 to 80 of about 4,025,166 (302)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Polish device for FOCCoS/PFS slit system
, 2014 The Fiber Optical Cable and Connector System, FOCCoS, for the Prime Focus Spectrograph, PFS, is responsible for transporting light from the Subaru Telescope focal plane to a set of four spectrographs. Each spectrograph will be fed by a convex curved slit
de Arruda, Marcio Vital +10 more
core +1 more source
On the Mechanism of the Step Coverage of Blanket Tungsten Chemical Vapor Deposition [PDF]
, 1993 In this study, computer modeling of the contact fill process with chemical vapor deposition, (CVD) of tungsten is usedto show the importance of several details on the quality of the fill process. The effect of surface curvature on the stepcoverage of CVD-
Hasper, A., Schmitz, J.E.J.
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Engineering ProceedingsThe study begins with a comprehensive experimental investigation into the cutting capability of SS 431 steel using abrasive water jet machining (AWJM), focusing on optimizing the process through a response surface methodology (RSM-BBD) approach ...
Balasubramaniyan Chandrasekaran +5 more
doaj +1 more source
, 1997 During epitaxial crystal growth a pattern that has initially been imprinted on a surface approximately reproduces itself after the deposition of an integer number of monolayers.
A. Pimpinelli +18 more
core +1 more source
Microscopic nanomechanical dissipation in gallium arsenide resonators [PDF]
, 2018 We report on a systematic study of nanomechanical dissipation in high-frequency (approximatively 300 MHz) gallium arsenide optomechanical disk resonators, in conditions where clamping and fluidic losses are negligible.
Allain, P. E. +8 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
MicromachinesEnhancing the operational efficacy of electrical discharge machining (EDM) is crucial for achieving optimal results in various engineering materials. This study introduces an innovative solution—the use of coated electrodes—representing a significant ...
Hoang-Vuong Pham +4 more
doaj +1 more source