Results 51 to 60 of about 320,765 (312)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Local hull-based surface construction of volumetric data from silhouettes [PDF]
, 2008 The marching cubes (MC) is a general method which can construct a surface of an object from its volumetric data generated using a shape from silhouette method. Although MC is efficient and straightforward to implement, a MC surface may have discontinuity
Tjahjadi, Tardi, Shin, Dongjoe
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Carbon EnergySubstituting the sluggish oxygen evolution reaction with a more thermodynamically favorable ethanol oxidation reaction (EOR) offers an opportunity to circumvent the efficiency loss in water splitting and metal‐air batteries.
Yong Beom Kim +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Donor Cornea Use in Scleral Surface Reconstruction [PDF]
, 2021 Objectives:To investigate the indications for and results of treating scleral surface problems with donor corneal grafts that are not used in keratoplasty surgery or are left over from keratoplasty.Materials and Methods:The records of 16 patients in whom
Selma Özbek-Uzman +3 more
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
The Complex Architecture of the Vault System of an Early Medieval Church
Heritage, 2023 The present work focuses on the solid modeling of the church of Santa Sofia in Benevento, Italy, and is related to a multidisciplinary research project that involved methods typical to both the humanities and mathematical engineering.
Enrico Babilio, Silvana Rapuano
doaj +1 more source
Façade structure reconstruction using spaceborne TomoSAR point clouds
, 2012 Very high resolution SAR tomography using multiple data stacks from different viewing angles enables us for the first time to generate 4D point clouds of the illuminated area from space with a point density comparable to LiDAR.
Muhammad Shahzad +5 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source