Results 51 to 60 of about 5,544,273 (297)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ground-Level Surface Reconstruction and Soil Volume Estimation in Construction Sites Using Marching Cubes Method

open access: yesApplied Sciences
Accurate environmental sensing is pivotal for advancing automation in construction, particularly in autonomous excavation. Precise 3D representations of complex and dynamic site geometries is essential for obstacle detection, progress monitoring, and ...
Fattah Hanafi Sheikhha   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Optimized Autonomous Drone Navigation Using Double Deep Q-Learning for Enhanced Real-Time 3D Image Capture

open access: yesDrones
The proposed system assists in the automatic creation of three-dimensional (3D) meshes for all types of objects, buildings, or scenarios, using drones with monocular RGB cameras.
Javier Sánchez-Soriano   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Surface profile prediction and analysis applied to turning process [PDF]

open access: yes, 2008
An approach for the prediction of surface profile in turning process using Radial Basis Function (RBF) neural networks is presented. The input parameters of the RBF networks are cutting speed, depth of cut and feed rate.
LU, Chen, COSTES, Jean-Philippe
core   +1 more source

Image-Based Multiresolution Implicit Object Modeling

open access: yesEURASIP Journal on Advances in Signal Processing, 2002
We discuss two image-based 3D modeling methods based on a multiresolution evolution of a volumetric function′s level set. In the former method, the role of the level set implosion is to fuse ("sew" and "stitch") together several partial ...
Sarti Augusto, Tubaro Stefano
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Façade structure reconstruction using spaceborne TomoSAR point clouds [PDF]

open access: yes, 2012
Very high resolution SAR tomography using multiple data stacks from different viewing angles enables us for the first time to generate 4D point clouds of the illuminated area from space with a point density comparable to LiDAR.
Muhammad Shahzad   +5 more
core   +1 more source

A New Method For Three Dimensional Cubic Bezier Surface Reconstruction Based On Matching The Surface Framework [PDF]

open access: yesEngineering and Technology Journal, 2010
Numerous efforts have been directed to convert the physical model ( in-handmodel) to a computer model. This work is dedicated for the cubic Bezier surfacereconstruction based on finding the positions of the sixteen control points that form thesurface of ...
Wissam K. Hamdan
doaj   +1 more source

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