Results 41 to 50 of about 274,881 (262)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A 3D Surface Reconstruction Pipeline for Plant Phenotyping

open access: yesRemote Sensing
Plant phenotyping plays a crucial role in crop science and plant breeding. However, traditional methods often involve time-consuming and manual observations.
Lina Stausberg   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Ground-Level Surface Reconstruction and Soil Volume Estimation in Construction Sites Using Marching Cubes Method

open access: yesApplied Sciences
Accurate environmental sensing is pivotal for advancing automation in construction, particularly in autonomous excavation. Precise 3D representations of complex and dynamic site geometries is essential for obstacle detection, progress monitoring, and ...
Fattah Hanafi Sheikhha   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Optimized Autonomous Drone Navigation Using Double Deep Q-Learning for Enhanced Real-Time 3D Image Capture

open access: yesDrones
The proposed system assists in the automatic creation of three-dimensional (3D) meshes for all types of objects, buildings, or scenarios, using drones with monocular RGB cameras.
Javier Sánchez-Soriano   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Image-Based Multiresolution Implicit Object Modeling

open access: yesEURASIP Journal on Advances in Signal Processing, 2002
We discuss two image-based 3D modeling methods based on a multiresolution evolution of a volumetric function′s level set. In the former method, the role of the level set implosion is to fuse ("sew" and "stitch") together several partial ...
Sarti Augusto, Tubaro Stefano
doaj   +1 more source

A New Method For Three Dimensional Cubic Bezier Surface Reconstruction Based On Matching The Surface Framework [PDF]

open access: yesEngineering and Technology Journal, 2010
Numerous efforts have been directed to convert the physical model ( in-handmodel) to a computer model. This work is dedicated for the cubic Bezier surfacereconstruction based on finding the positions of the sixteen control points that form thesurface of ...
Wissam K. Hamdan
doaj   +1 more source

Surface Reconstruction in Crystals

open access: yesPhysical Review Letters, 1983
Proposition d'un modele montrant a la fois une transition de phase reconstructive en surface et une transition de facettage, dependant des parametres ...
openaire   +1 more source

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