Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Absolute radiometric calibration with lunar surface reflectance as reference for earth-observing VNIR camera. [PDF]
Heliyon, 2022 Tan W, Wang X, He H, Qi W.
europepmc +1 more source
Outage Analysis for Intelligent Reflecting Surface Assisted Vehicular Communication Networks [PDF]
, 2020 Jue Wang +4 more
openalex +1 more source
Effects of aerosols and surface shadowing on bidirectional reflectance measurements of deserts [PDF]
Desert surfaces are probably one of the most stable of the Earth's natural targets for remote sensing. The bidirectional reflectance properties of the Saudi Arabian desert was investigated during the Summer Monsoon Experiment (Summer Monex). A comparison
Bowker, David E., Davis, Richard E.
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Robust Design for Intelligent Reflecting Surface Assisted MIMO-OFDMA Terahertz Communications [PDF]
, 2020 Wanming Hao +6 more
openalex +1 more source
Intelligent Reflecting Surface Assisted Localization: Opportunities and Challenges [PDF]
, 2022 Samarendra Nath Sur +4 more
openalex +1 more source
Using Simulated Micrometeoroid Impacts to Understand the Progressive Space Weathering of the Surface of Mercury [PDF]
The surfaces of airless bodies such as Mercury are continually modified by space weathering, which is driven by micrometeoroid impacts and solar wind irradiation.
Loeffler, M. J. +4 more
core +1 more source
On the effect of thin film growth mechanisms on the specular reflectance of aluminum thin films deposited via filtered cathodic vacuum arc [PDF]
, 2018 The optimisation of the specular reflectance of solar collectors is a key parameter to increase the global yield of concentrated solar power (CSP) plants.
Escobar-Galindo, Ramón +5 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source